Actively Recruiting

Age: 18Years - 130Years
FEMALE
NCT04830709

Non-interventional Study to Collect Real-world Clinical and Patient-reported Outcomes in Ovarian Cancer

Led by AstraZeneca · Updated on 2026-04-22

750

Participants Needed

93

Research Sites

615 weeks

Total Duration

On this page

Sponsors

A

AstraZeneca

Lead Sponsor

N

North-Eastern German Society of Gynecological Oncology e.V. (NOGGO e.V.)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This prospective non-interventional study is intended to generate new data and insights into first-line (1L) treatment of newly diagnosed advanced high-grade epithelial Ovarian cancer (OC) in Germany relevant for patients, physicians and payers. It will capture the influence of 1L Poly ADP ribose polymerase inhibitor (PARPi) maintenance treatment (MTX) on medical routine in Germany, especially on: * outcome of the 3-steps 1L treatment phase (including surgery, Chemotherapy (CTX) and MTX) including the potential of patients with primary advanced OC to be cured, * patient's follow-up (FU) during and after MTX therapy, * patient-reported outcomes (PROs), experiences and needs, * physician's experience, * BRCA/HRD and genomic scar testing behavior at diagnosis/during 1L therapy, * patient selection for different 1L systemic treatment approaches, * use and safety of drugs, * treatment sequence in case of recurrence

CONDITIONS

Official Title

Non-interventional Study to Collect Real-world Clinical and Patient-reported Outcomes in Ovarian Cancer

Who Can Participate

Age: 18Years - 130Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed written informed consent
  • Women aged 18 years or older
  • Newly diagnosed with primary advanced (FIGO stages III and IV) high-grade epithelial ovarian cancer, including fallopian tube and/or primary peritoneal cancer
  • All surgical procedures completed prior to enrollment for patients qualifying for primary debulking surgery
  • BRCA mutation testing performed or planned
  • Planned first-line platinum-based chemotherapy or a maximum of 3 cycles received with no disease progression
  • Enrollment after completion of surgery and at first post-surgery chemotherapy cycle if neoadjuvant chemotherapy was given
  • Willing and able to report patient-reported outcomes electronically
  • Women of childbearing potential must use two reliable forms of contraception according to standard care
Not Eligible

You will not qualify if you...

  • Pregnancy or breast-feeding
  • Current or planned participation in an interventional clinical trial on first-line ovarian cancer treatment
  • Current or planned systemic treatment for tumors other than ovarian cancer
  • Not eligible for platinum-based chemotherapy or early progression during first-line chemotherapy cycles before enrollment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 93 locations

1

Research Site

Böblingen, Germany, Germany, 71032

Actively Recruiting

2

Research Site

Göttingen, Germany, Germany, 37075

Actively Recruiting

3

Research Site

Nürtingen, Germany, Germany, 72622

Actively Recruiting

4

Research Site

Osnabrück, Germany, Germany, 49076

Actively Recruiting

5

Research Site

Rotenburg (W Mme), Germany, Germany, 27356

Actively Recruiting

6

Research Site

Schwäbisch Hall, Germany, Germany, 74523

Withdrawn

7

Research Site

Aachen, Germany, 52074

Actively Recruiting

8

Research Site

Amberg, Germany, 92224

Actively Recruiting

9

Research Site

Aschaffenburg, Germany, 63739

Actively Recruiting

10

Research Site

Augsburg, Germany, 86156

Actively Recruiting

11

Research Site

Baden-Baden, Germany, 76532

Withdrawn

12

Research Site

Bayreuth, Germany, 95445

Actively Recruiting

13

Research Site

Berlin, Germany, 10367

Actively Recruiting

14

Research Site

Berlin, Germany, 10967

Actively Recruiting

15

Research Site

Berlin, Germany, 12101

Actively Recruiting

16

Research Site

Berlin, Germany, 12559

Actively Recruiting

17

Research Site

Berlin, Germany, 13187

Actively Recruiting

18

Research Site

Berlin, Germany, 13353

Actively Recruiting

19

Research Site

Berlin, Germany, 13509

Actively Recruiting

20

Research Site

Berlin, Germany, 14163

Actively Recruiting

21

Research Site

Berlin, Germany, 14169

Actively Recruiting

22

Research Site

Bielefeld, Germany, 33604

Actively Recruiting

23

Research Site

Bielefeld, Germany, 33611

Actively Recruiting

24

Research Site

Bochum, Germany, 44791

Actively Recruiting

25

Research Site

Bonn, Germany, 53113

Actively Recruiting

26

Research Site

Borna, Germany, 4552

Actively Recruiting

27

Research Site

Bottrop, Germany, 46236

Actively Recruiting

28

Research Site

Brandenburg an der Havel, Germany, 14770

Actively Recruiting

29

Research Site

Bremen, Germany, 28205

Actively Recruiting

30

Research Site

Coburg, Germany, 96450

Actively Recruiting

31

Research Site

Cologne, Germany, 50931

Actively Recruiting

32

Research Site

Cologne, Germany, 50935

Actively Recruiting

33

Research Site

Dessau, Germany, 6947

Actively Recruiting

34

Research Site

Donauwörth, Germany, 86609

Withdrawn

35

Research Site

Dortmund, Germany, 44137

Actively Recruiting

36

Research Site

Dresden, Germany, 1307

Actively Recruiting

37

Research Site

Düsseldorf, Germany, 40489

Actively Recruiting

38

Research Site

Eggenfelden, Germany, 84307

Actively Recruiting

39

Research Site

Erfurt, Germany, 99084

Actively Recruiting

40

Research Site

Fürth, Germany, 90766

Actively Recruiting

41

Research Site

Gelnhausen, Germany, 63571

Actively Recruiting

42

Research Site

Gera, Germany, 7548

Actively Recruiting

43

Research Site

Halle, Germany, 6110

Actively Recruiting

44

Research Site

Hamburg, Germany, 20246

Actively Recruiting

45

Research Site

Hamburg, Germany, 20357

Withdrawn

46

Research Site

Hamburg, Germany, 22307

Actively Recruiting

47

Research Site

Hamburg, Germany, 22457

Actively Recruiting

48

Research Site

Hanau, Germany, 63450

Actively Recruiting

49

Research Site

Heilbronn, Germany, 74078

Actively Recruiting

50

Research Site

Hildesheim, Germany, 31134

Actively Recruiting

51

Research Site

Homburg, Germany, 66421

Actively Recruiting

52

Research Site

Itzehoe, Germany, 25524

Actively Recruiting

53

Research Site

Jena, Germany, 7747

Actively Recruiting

54

Research Site

Kiel, Germany, 24116

Actively Recruiting

55

Research Site

Krefeld, Germany, 47805

Actively Recruiting

56

Research Site

Leipzig, Germany, 4103

Actively Recruiting

57

Research Site

Limburg, Germany, 65549

Actively Recruiting

58

Research Site

Lübeck, Germany, 23562

Actively Recruiting

59

Research Site

Magdeburg, Germany, 39108

Actively Recruiting

60

Research Site

Magdeburg, Germany, 39130

Actively Recruiting

61

Research Site

Mainz, Germany, 55131

Actively Recruiting

62

Research Site

Mönchengladbach, Germany, 41061

Actively Recruiting

63

Research Site

Mutlangen, Germany, 73557

Actively Recruiting

64

Research Site

München, Germany, 80638

Actively Recruiting

65

Research Site

Münster, Germany, 48145

Actively Recruiting

66

Research Site

Nuremberg, Germany, 90419

Actively Recruiting

67

Research Site

Offenburg, Germany, 77654

Actively Recruiting

68

Research Site

Pforzheim, Germany, 75179

Actively Recruiting

69

Research Site

Plauen, Germany, 08525

Actively Recruiting

70

Research Site

Potsdam, Germany, 14467

Actively Recruiting

71

Research Site

Recklinghausen, Germany, 45659

Actively Recruiting

72

Research Site

Regensburg, Germany, 93053

Actively Recruiting

73

Research Site

Rheine, Germany, 48431

Actively Recruiting

74

Research Site

Rosenheim, Germany, 83022

Actively Recruiting

75

Research Site

Rostock, Germany, 18059

Actively Recruiting

76

Research Site

Saarlouis, Germany, 66740

Actively Recruiting

77

Research Site

Siegen, Germany, 57072

Actively Recruiting

78

Research Site

Singen, Germany, 78224

Actively Recruiting

79

Research Site

Solingen, Germany, 42653

Actively Recruiting

80

Research Site

Stendal, Germany, 39576

Actively Recruiting

81

Research Site

Stralsund, Germany, 18439

Actively Recruiting

82

Research Site

Stuttgart, Germany, 70174

Actively Recruiting

83

Research Site

Stuttgart, Germany, 70199

Actively Recruiting

84

Research Site

Torgau, Germany, 4860

Actively Recruiting

85

Research Site

Traunstein, Germany, 83278

Actively Recruiting

86

Research Site

Ulm, Germany, 89075

Actively Recruiting

87

Research Site

Villingen-Schwenningen, Germany, 78052

Actively Recruiting

88

Research Site

Wiesbaden, Germany, 65199

Actively Recruiting

89

Research Site

Winnenden, Germany, 71364

Actively Recruiting

90

Research Site

Witten, Germany, 58452

Actively Recruiting

91

Research Site

Wolfsburg, Germany, 38440

Actively Recruiting

92

Research Site

Worms, Germany, 67550

Actively Recruiting

93

Research Site

Wuppertal, Germany, 42283

Actively Recruiting

Loading map...

Research Team

A

AstraZeneca Clinical Study Information Center

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Non-interventional Study to Collect Real-world Clinical and Patient-reported Outcomes in Ovarian Cancer | DecenTrialz