Actively Recruiting

Age: 18Years - 99Years
All Genders
NCT06551519

A Non-interventional Study Evaluating Clinical Utility and Implications on Improved Patient Management of Serum Neurofilament as a Prognostic Marker for Disease Activity in Patients With Relapsing Multiple Sclerosis

Led by Novartis Pharmaceuticals · Updated on 2026-04-01

700

Participants Needed

109

Research Sites

213 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective, multicenter, observational, non-interventional study (NIS) in patients with Multiple Sclerosis (MS) and routinely assessed serum neurofilament light (sNfL) values in Germany

CONDITIONS

Official Title

A Non-interventional Study Evaluating Clinical Utility and Implications on Improved Patient Management of Serum Neurofilament as a Prognostic Marker for Disease Activity in Patients With Relapsing Multiple Sclerosis

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Provide written informed consent before participation
  • Have relapsing multiple sclerosis and be 18 years or older
  • Have been treated with EU-approved category 1 disease-modifying therapies for MS for at least 3 months
  • Have a serum neurofilament light (sNfL) test result from a commercially available test within the last 3 months
Not Eligible

You will not qualify if you...

  • Receiving treatment outside the approved label of the respective disease-modifying therapy
  • Participating in any interventional study or another Novartis non-interventional study with ofatumumab

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 109 locations

1

Novartis Investigative Site

Albstadt, Baden-Wurttemberg, Germany, 72458

Actively Recruiting

2

Novartis Investigative Site

Hettingen, Baden-Wurttemberg, Germany, 72513

Actively Recruiting

3

Novartis Investigative Site

Mannheim, Baden-Wurttemberg, Germany, 68163

Actively Recruiting

4

Novartis Investigative Site

Schwetzingen, Baden-Wurttemberg, Germany, 68723

Actively Recruiting

5

Novartis Investigative Site

Bamberg, Bavaria, Germany, 96052

Actively Recruiting

6

Novartis Investigative Site

Neuburg A.d. Donau, Bavaria, Germany, 86633

Actively Recruiting

7

Novartis Investigative Site

Regensburg, Bavaria, Germany, 93059

Actively Recruiting

8

Novartis Investigative Site

Unterhaching, Bavaria, Germany, 82008

Actively Recruiting

9

Novartis Investigative Site

Untermeitingen, Bavaria, Germany, 86836

Actively Recruiting

10

Novartis Investigative Site

Weiden in Der Oberpfalz, Bavaria, Germany, 92637

Actively Recruiting

11

Novartis Investigative Site

Wolfratshausen, Bavaria, Germany, 82515

Withdrawn

12

Novartis Investigative Site

Hamburg, Free and Hanseatic City of Hamburg, Germany, 22297

Actively Recruiting

13

Novartis Investigative Site

Bad Homburg, Hesse, Germany, 61348

Actively Recruiting

14

Novartis Investigative Site

Frankfurt am Main, Hesse, Germany, 60311

Actively Recruiting

15

Novartis Investigative Site

Frankfurt am Main, Hesse, Germany, 65929

Actively Recruiting

16

Novartis Investigative Site

Kassel, Hesse, Germany, 34121

Actively Recruiting

17

Novartis Investigative Site

Schwalmstadt, Hesse, Germany, 34613

Actively Recruiting

18

Novartis Investigative Site

Quakenbrück, Lower Saxony, Germany, 49610

Actively Recruiting

19

Novartis Investigative Site

Dortmund, North Rhine-Westphalia, Germany, 44135

Actively Recruiting

20

Novartis Investigative Site

Dortmund, North Rhine-Westphalia, Germany, 44287

Actively Recruiting

21

Novartis Investigative Site

Gelsenkirchen, North Rhine-Westphalia, Germany, 45894

Actively Recruiting

22

Novartis Investigative Site

Meerbusch, North Rhine-Westphalia, Germany, 40667

Actively Recruiting

23

Novartis Investigative Site

Siegen, North Rhine-Westphalia, Germany, 57072

Actively Recruiting

24

Novartis Investigative Site

Sundern Sauerland, North Rhine-Westphalia, Germany, 59846

Actively Recruiting

25

Novartis Investigative Site

Chemnitz, Saxony, Germany, 09117

Actively Recruiting

26

Novartis Investigative Site

Dresden, Saxony, Germany, 01307

Actively Recruiting

27

Novartis Investigative Site

Görlitz, Saxony, Germany, 02828

Actively Recruiting

28

Novartis Investigative Site

Leipzig, Saxony, Germany, 04299

Actively Recruiting

29

Novartis Investigative Site

Leipzig, Saxony, Germany, 04315

Actively Recruiting

30

Novartis Investigative Site

Altenburg, Thuringia, Germany, 04600

Actively Recruiting

31

Novartis Investigative Site

Jena, Thuringia, Germany, 07740

Actively Recruiting

32

Novartis Investigative Site

Mühlhausen, Thuringia, Germany, 99974

Actively Recruiting

33

Novartis Investigative Site

Aalen, Germany, 73433

Actively Recruiting

34

Novartis Investigative Site

Altenholz, Germany, 24161

Actively Recruiting

35

Novartis Investigative Site

Alzey, Germany, 55232

Withdrawn

36

Novartis Investigative Site

Aschaffenburg, Germany, 63739

Actively Recruiting

37

Novartis Investigative Site

Augsburg, Germany, 86150

Actively Recruiting

38

Novartis Investigative Site

Backnang, Germany, 71522

Actively Recruiting

39

Novartis Investigative Site

Bad Krozingen, Germany, 79189

Actively Recruiting

40

Novartis Investigative Site

Bergneustadt, Germany, 51702

Actively Recruiting

41

Novartis Investigative Site

Berlin, Germany, 10437

Actively Recruiting

42

Novartis Investigative Site

Berlin, Germany, 12099

Actively Recruiting

43

Novartis Investigative Site

Berlin, Germany, 12163

Actively Recruiting

44

Novartis Investigative Site

Berlin, Germany, 12167

Withdrawn

45

Novartis Investigative Site

Berlin, Germany, 14057

Actively Recruiting

46

Novartis Investigative Site

Berlin, Germany, 14169

Actively Recruiting

47

Novartis Investigative Site

Bielefeld, Germany, 33647

Completed

48

Novartis Investigative Site

Bochum, Germany, 44787

Actively Recruiting

49

Novartis Investigative Site

Bogen, Germany, 94327

Actively Recruiting

50

Novartis Investigative Site

Bonn, Germany, 53111

Actively Recruiting

51

Novartis Investigative Site

Chemnitz, Germany, 09117

Actively Recruiting

52

Novartis Investigative Site

Coburg, Germany, 96450

Actively Recruiting

53

Novartis Investigative Site

Crailsheim, Germany, 74564

Actively Recruiting

54

Novartis Investigative Site

Dessau, Germany, 06846

Actively Recruiting

55

Novartis Investigative Site

Dierdorf, Germany, 56269

Actively Recruiting

56

Novartis Investigative Site

Dillingen Saar, Germany, 66763

Actively Recruiting

57

Novartis Investigative Site

Dresden, Germany, 01067

Actively Recruiting

58

Novartis Investigative Site

Duisburg, Germany, 47138

Actively Recruiting

59

Novartis Investigative Site

Düsseldorf, Germany, 40211

Actively Recruiting

60

Novartis Investigative Site

Düsseldorf, Germany, 40237

Actively Recruiting

61

Novartis Investigative Site

Düsseldorf, Germany, 40625

Actively Recruiting

62

Novartis Investigative Site

Eisleben Lutherstadt, Germany, 06295

Actively Recruiting

63

Novartis Investigative Site

Eltville, Germany, 65343

Withdrawn

64

Novartis Investigative Site

Erbach im Odenwald, Germany, 64711

Actively Recruiting

65

Novartis Investigative Site

Erfurt, Germany, 99096

Actively Recruiting

66

Novartis Investigative Site

Essen, Germany, 45138

Actively Recruiting

67

Novartis Investigative Site

Essen, Germany, 45257

Actively Recruiting

68

Novartis Investigative Site

Gelsenkirchen, Germany, 45879

Actively Recruiting

69

Novartis Investigative Site

Gera, Germany, 07548

Actively Recruiting

70

Novartis Investigative Site

Göttingen, Germany, 37073

Actively Recruiting

71

Novartis Investigative Site

Hagen, Germany, 58099

Actively Recruiting

72

Novartis Investigative Site

Hamburg, Germany, 22179

Actively Recruiting

73

Novartis Investigative Site

Hanover, Germany, 30159

Actively Recruiting

74

Novartis Investigative Site

Heidenheim, Germany, 89518

Actively Recruiting

75

Novartis Investigative Site

Herford, Germany, 32049

Actively Recruiting

76

Novartis Investigative Site

Hoppegarten, Germany, 15366

Actively Recruiting

77

Novartis Investigative Site

Höxter, Germany, 37671

Actively Recruiting

78

Novartis Investigative Site

Itzehoe, Germany, 25524

Actively Recruiting

79

Novartis Investigative Site

Karlsruhe, Germany, 76133

Actively Recruiting

80

Novartis Investigative Site

Katzenelnbogen, Germany, 56368

Actively Recruiting

81

Novartis Investigative Site

Leipzig, Germany, 04109

Actively Recruiting

82

Novartis Investigative Site

Lüneburg, Germany, 21335

Actively Recruiting

83

Novartis Investigative Site

Magdeburg, Germany, 39104

Withdrawn

84

Novartis Investigative Site

Magdeburg, Germany, 39120

Actively Recruiting

85

Novartis Investigative Site

Merzig, Germany, 66663

Actively Recruiting

86

Novartis Investigative Site

Minden, Germany, 32423

Actively Recruiting

87

Novartis Investigative Site

München, Germany, 80939

Actively Recruiting

88

Novartis Investigative Site

München, Germany, 81675

Actively Recruiting

89

Novartis Investigative Site

Münster, Germany, 48149

Actively Recruiting

90

Novartis Investigative Site

Neuwied, Germany, 56564

Actively Recruiting

91

Novartis Investigative Site

Osnabrück, Germany, 49074

Actively Recruiting

92

Novartis Investigative Site

Pforzheim, Germany, 75172

Actively Recruiting

93

Novartis Investigative Site

Remscheid, Germany, 42853

Actively Recruiting

94

Novartis Investigative Site

Rülzheim, Germany, 76761

Actively Recruiting

95

Novartis Investigative Site

Salzatal, Germany, 06198

Actively Recruiting

96

Novartis Investigative Site

Schiltach, Germany, 77761

Withdrawn

97

Novartis Investigative Site

Schwäbisch Hall, Germany, 74523

Actively Recruiting

98

Novartis Investigative Site

Siegen, Germany, 57076

Actively Recruiting

99

Novartis Investigative Site

Singen, Germany, 78224

Actively Recruiting

100

Novartis Investigative Site

Sinsheim, Germany, 74889

Actively Recruiting

101

Novartis Investigative Site

Stadtroda, Germany, 07646

Actively Recruiting

102

Novartis Investigative Site

Stuttgart, Germany, 70174

Actively Recruiting

103

Novartis Investigative Site

Stuttgart, Germany, 70178

Withdrawn

104

Novartis Investigative Site

Tirschenreuth, Germany, 95643

Actively Recruiting

105

Novartis Investigative Site

Ulm, Germany, 89073

Actively Recruiting

106

Novartis Investigative Site

Velbert, Germany, 42551

Actively Recruiting

107

Novartis Investigative Site

Weil der Stadt, Germany, 71263

Actively Recruiting

108

Novartis Investigative Site

Witten, Germany, 58452

Actively Recruiting

109

Novartis Investigative Site

Wolfenbüttel, Germany, 38300

Actively Recruiting

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Research Team

N

Novartis Pharmaceuticals

CONTACT

N

Novartis Pharmaceuticals

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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