Actively Recruiting
A Non-Interventional Study in Participants With Indolent Systemic Mastocytosis (ISM) in Germany
Led by Blueprint Medicines Corporation · Updated on 2026-04-20
80
Participants Needed
8
Research Sites
155 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a non-interventional study assessing the effectiveness of avapritinib (BLU-285) in the management of ISM in real-world settings in Germany. The study also seeks to address the existing data gap in the natural history and management of participants with ISM. The study is designed to follow each participant up to a maximum of 24 months.
CONDITIONS
Official Title
A Non-Interventional Study in Participants With Indolent Systemic Mastocytosis (ISM) in Germany
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Starting avapritinib treatment for indolent systemic mastocytosis with moderate to severe symptoms not controlled by symptomatic treatment
- Treatment decision made by healthcare provider as part of routine care
- Treatment in accordance with approved prescribing information
- Adults aged 18 years or older
You will not qualify if you...
- History of vascular aneurysm, intracranial hemorrhage, stroke within the past year, or severe thrombocytopenia
- Previous use of avapritinib as a commercial drug or in a clinical study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 8 locations
1
Charité Universitätmedizin Berlin, Klinik für Dermatologie, Venerologie und Allergologie
Berlin, Germany, 10117
Actively Recruiting
2
Katholisches Klinikum Bochum
Bochum, Germany, 44791
Actively Recruiting
3
MVZ Klinikum Deggendorf
Deggendorf, Germany, 94469
Actively Recruiting
4
Universitätsklinikum Carl Gustav Carus Dresden Klinik und Poliklinik für Dermatologie
Dresden, Germany, 01307
Actively Recruiting
5
University Medical Center Goettingen - Georg August University of Goettingen
Göttingen, Germany, 37075
Actively Recruiting
6
Universitats-Hautklinik Tubingen, Studienzentrum lmmundermatologie
Tübingen, Germany, 72076
Actively Recruiting
7
HNO-Gemeinschaftspraxis Wiesbaden, GEKA Gesellschaft für Experimentelle und Klinische Atemwegsforschung mbH, Zentrum für Rhinologie und Allergologie
Wiesbaden, Germany, 65205
Actively Recruiting
8
Helios Universitätsklinikum Wuppertal
Wuppertal, Germany, 42283
Actively Recruiting
Research Team
B
Blueprint Medicines, EU Contact
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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