Actively Recruiting

Phase Not Applicable
Age: 55Years +
All Genders
NCT05661084

Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia

Led by Hebrew SeniorLife · Updated on 2026-01-12

144

Participants Needed

1

Research Sites

240 weeks

Total Duration

On this page

Sponsors

H

Hebrew SeniorLife

Lead Sponsor

B

BrightFocus Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

This project aims to examine the efficacy of remote, caregiver-led tES/brain stimulation intervention targeted to improve memory, mobility, and executive functioning among older adults with mild cognitive impairment or mild dementia.

CONDITIONS

Official Title

Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia

Who Can Participate

Age: 55Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants willing and able to give informed consent after explanation
  • Participants able and willing to comply with all study requirements
  • Participants must sign an informed consent form
  • Participants able to read, write, and communicate in English
  • Caregiver/Administrator must be at least 18 years old
  • Caregiver/Administrator able to read, write, and communicate in English
  • Caregiver/Administrator must report computer proficiency and willingness to learn to administer tES
  • Caregiver/Administrator must be available on weekdays to administer tES during the study period
Not Eligible

You will not qualify if you...

  • Participants with major psychiatric disorders like major depressive disorder, schizophrenia, or psychosis
  • Participants who are blind or have disabilities preventing task performance
  • Participants with contraindications to tES such as recent seizures, use of neuroactive drugs, or implanted medical devices
  • Participants with active scalp skin conditions such as eczema
  • Participants scoring 18 or less on the Montreal Cognitive Assessment during screening
  • Participants unable to understand study procedures after informed consent review
  • Caregivers with mild cognitive impairment (MoCA score less than or equal to 26)
  • Caregivers unable to understand study procedures after informed consent review
  • Caregivers with poor eyesight, severe arthritis, pain, deformity, or other conditions interfering with tES administration

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hinda and Arthur Marcus Institute for Aging Research

Boston, Massachusetts, United States, 02131

Actively Recruiting

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Research Team

H

HomeStim Study

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia | DecenTrialz