Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06874309

Non-invasive Brain Stimulation to Prepare the Patient for Bariatric Surgery (REBAS)

Led by Masaryk University · Updated on 2025-03-13

65

Participants Needed

2

Research Sites

191 weeks

Total Duration

On this page

Sponsors

M

Masaryk University

Lead Sponsor

S

St. Anne's University Hospital Brno, Czech Republic

Collaborating Sponsor

AI-Summary

What this Trial Is About

Obesity is a chronic metabolic condition characterized by excessive accumulation of body fat, which triggers physiological mechanisms that increase the risk of a wide range of health problems. The most effective treatment for severe obesity is metabolic-bariatric surgery, which can lead to a 15-20% weight reduction, significantly lowering the risks of illness and death. However, the success of this surgery can be threatened by poor eating habits after the procedure. The main goal of this study is to enhance the long-term effectiveness of bariatric surgery by combining it with non-invasive brain stimulation (tDCS) targeting inhibitory centers before the operation. Additionally, the investigators aim to comprehensively monitor patients before and after surgery, focusing on investigating changes in brain function associated with the achieved weight loss.

CONDITIONS

Official Title

Non-invasive Brain Stimulation to Prepare the Patient for Bariatric Surgery (REBAS)

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 65 with severe or morbid obesity (BMI over 35 or 40 kg/m2)
  • Eligible for bariatric surgery according to current guidelines
  • Reduced control over eating behavior as shown in the Eating Habits Questionnaire
Not Eligible

You will not qualify if you...

  • Unable to provide informed consent or cooperate with study procedures
  • Personal history of ischemic heart disease, myocardial infarction, stroke, heart failure, or atrial fibrillation
  • Previous bariatric surgery
  • Pregnant or planning pregnancy during the study
  • Deemed unsuitable for the study by a physician or neuropsychologist
  • Having dreadlocks preventing EEG use

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Saint Anne's University Hospital

Brno, Czechia, Czechia, 60200

Actively Recruiting

2

Central European Institute of Technology Masaryk University

Brno, Czechia, Czechia, 62500

Actively Recruiting

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Research Team

P

Petra Holštajn Zemánková, Dr.

CONTACT

S

Sylvie Kropáčová, Dr.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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