Actively Recruiting
Non-invasive Detection of Volatile Metabolites in Parkinson's Disease
Led by Imperial College London · Updated on 2024-06-13
120
Participants Needed
1
Research Sites
105 weeks
Total Duration
On this page
Sponsors
I
Imperial College London
Lead Sponsor
I
Imperial College Healthcare NHS Trust
Collaborating Sponsor
AI-Summary
What this Trial Is About
Parkinson's disease (PD) is the second most common neurodegenerative disorder. Currently, a diagnostic test for early PD does not exist. The aim to address this problem by developing a non-invasive breath test to differentiate early PD from controls. Small molecules contained in breath, which offers precious information about disease presence, will be analysed. Data from the breath molecules and gut bacterial changes occurring in PD will be combined. These bacterial changes have been shown to arise years before the development of PD symptoms. Thanks to earlier diagnosis, therapies could start in advance and improve clinical outcomes and quality of life.
CONDITIONS
Official Title
Non-invasive Detection of Volatile Metabolites in Parkinson's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients undergoing neurological examination for confirmed or suspected Parkinson's disease
- Patients aged 6518 years and below 90 years of age
- Patients off antibiotic or probiotic therapies for at least the last 4 weeks
- Patients without formal diagnosis of dysbiotic conditions
- Patients with capacity
- Healthy volunteers, including partners or carers of Parkinson's patients
- Volunteers aged 6518 years and below 90 years of age
- Volunteers off antibiotic or probiotic therapies for at least the last 4 weeks
- Volunteers without formal diagnosis of dysbiotic conditions
- Volunteers with capacity
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
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Trial Site Locations
Total: 1 location
1
Charing Cross Hospital, Imperial College London
London, United Kingdom, W12 0NN
Actively Recruiting
Research Team
I
Ilaria Belluomo, Dr
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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