Actively Recruiting
Non-Invasive Diagnosis and Monitoring of Cardiac Masses by Liquid Biopsy
Led by Niguarda Hospital · Updated on 2026-04-15
26
Participants Needed
1
Research Sites
126 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a nonprofit, observational, prospective and retrospective,multicenter study in a population of young and adult patients ≥12 years with a diagnosis of a cardiac mass. The study will include both patients with masses of unknown pathological diagnosis and patients with a known histology of benign or malignant tumors. We predict a case-control allocation ratio of 1:1 between cardiac malignant tumors and benign lesions. Peripheral blood will be collected at participating centers during routine venipuncture,processed and then shipped for liquid biopsy ctDNA NGS analyses. If available, in malignant cases, matched tumor tissue samples collected as per clinical practice solid biopsies or surgery will be used for analyses. Longitudinal tracking through serial blood draws could be performed in selected cases of patients with cardiac malignancies who receive cancer treatment
CONDITIONS
Official Title
Non-Invasive Diagnosis and Monitoring of Cardiac Masses by Liquid Biopsy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 2 years old or older
- Suspected or confirmed diagnosis of a cardiac mass of any nature as assessed by standard clinical, radiological and/or pathological procedures.
You will not qualify if you...
- Inability of the patient to fully understand and sign the informed consent.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Niguarda Hospital
Milan, Italia, Italy, 20262
Actively Recruiting
Research Team
K
Katia Bencardino, MD
CONTACT
G
Giorgio Patelli, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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