Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT05433129

Non-Invasive Mapping of Cerebral Autoregulation Using Near Infrared Spectroscopy

Led by University of Manitoba · Updated on 2026-01-06

250

Participants Needed

1

Research Sites

233 weeks

Total Duration

On this page

Sponsors

U

University of Manitoba

Lead Sponsor

H

Health Sciences Centre, Winnipeg, Manitoba

Collaborating Sponsor

AI-Summary

What this Trial Is About

The investigators propose to employ advanced multi-channel near non-invasive near infrared spectroscopy (NIRS) system married with entirely non-invasive continuous arterial blood pressure (niABP) monitor to create a new wearable and portable imaging system that derives CA maps of the entire brain with high sampling rates at each point. The objectives of this project are as follows: 1. To perform in vivo testing and optimization of the device using a block-trial design to evaluate the CA mapping system's performance during various perturbations. 2. To explore the impact of aging and sex on regional disparities in CA in a healthy volunteer population using static recording along with perturbation testing.

CONDITIONS

Official Title

Non-Invasive Mapping of Cerebral Autoregulation Using Near Infrared Spectroscopy

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy volunteers (male and female)
  • Age > 17
Not Eligible

You will not qualify if you...

  • History of neurological illness
  • History of systemic vascular disease
  • History of cerebrovascular disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Health Sciences Centre (HSC)

Winnipeg, Manitoba, Canada, R3A 1R9

Actively Recruiting

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Research Team

F

Frederick A Zeiler, MD PhD FRCSC

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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