Actively Recruiting
Non-invasive Mapping-Guided Atrial Fibrillation Ablation
Led by Hospital Clinic of Barcelona · Updated on 2026-01-22
30
Participants Needed
1
Research Sites
99 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this pilot study is to test if noninvasive global mapping can guide catheter ablation defining personalized targets and improve the therapy of atrial fibrillation. It will also test the safety of such an approach. The main questions it aims to answer are: * Does ablation of targets defined by noninvasive global mapping improve rates of acute atrial fibrillation termination? * Does such a personalized ablation approach reduce arrhythmia recurrence rates? Researchers will compare the results of the personalized ablation approach with comparable patients that had undergone a conventional "empirical" ablation approach (pulmonary vein isolation). Participants will: * Undergo a personalized catheter ablation approach employing both a noninvasive global mapping system and a conventional intracardiac mapping system * Visit the clinic 3, 6 and 12 months after ablation for clinical follow-up * Schedule a telephone visit 9 and 24 months after ablation for clinical follow-up
CONDITIONS
Official Title
Non-invasive Mapping-Guided Atrial Fibrillation Ablation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ablation-na�efve patients with persistent atrial fibrillation planned for catheter ablation
- Left atrial enlargement defined by LA diameter 645 mm or LA volume index 635 ml/m2 or LA area 620 cm2
You will not qualify if you...
- Previous cardiac ablation
- Age under 18 years
- Pregnancy or lactation
- Previous stroke or transient ischemic attack (TIA)
- Severe left ventricular dysfunction with ejection fraction under 35%
- Renal failure with glomerular filtration rate under 30 ml/min
- Skin conditions or allergies increasing risk of irritation or rash
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Hospital Clinic, University of Barcelona
Barcelona, Spain, 08036
Actively Recruiting
Research Team
T
Till F Althoff, M.D.
CONTACT
I
Ivo Roca-Luque, M.D., Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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