Actively Recruiting
Non-Invasive Method for Evaluation of Cardiac Resynchronization Therapy
Led by Oslo University Hospital · Updated on 2025-08-06
80
Participants Needed
1
Research Sites
414 weeks
Total Duration
On this page
Sponsors
O
Oslo University Hospital
Lead Sponsor
S
South-Eastern Norway Regional Health Authority
Collaborating Sponsor
AI-Summary
What this Trial Is About
Left bundle branch block (LBBB) exists in about 25% of patients with congestive heart failure and is associated with worsened prognosis. Cardiac resynchronization therapy (CRT) has been one of the most important advancements in the past two decades for patients with LBBB heart failure. However, 30-40% of patients receiving a CRT do not benefit from it. In this study, the investigators will test a noninvasive device to evaluate acute effect of CRT during implantation and at follow-up CRT controls. In addition, echocardiography will be performed during CRT turned ON and OFF to visualize the changes in intraventricular flow and functional parameters of the heart.
CONDITIONS
Official Title
Non-Invasive Method for Evaluation of Cardiac Resynchronization Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients referred for CRT implantation or follow-up based on European Society of Cardiology guidelines
- Sinus rhythm
- New York Heart Association class II or III heart failure
- Left bundle branch block
- QRS duration 130 ms or longer
- Left ventricular ejection fraction 40% or less
- Echocardiography exam before implantation
- Informed consent given
You will not qualify if you...
- Younger than 18 years or older than 80 years
- Ongoing atrial fibrillation
- Complete atrioventricular block
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Oslo University Hospital
Oslo, Norway, 0372
Actively Recruiting
Research Team
E
Espen W. Remme, Dr.ing
CONTACT
M
Marit Witsø, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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