Actively Recruiting
Non-Invasive Neuromodulation for Upper Extremity Function in Spinal Cord Injury: A Crossover Trial
Led by University of Alberta · Updated on 2025-05-22
10
Participants Needed
1
Research Sites
255 weeks
Total Duration
On this page
Sponsors
U
University of Alberta
Lead Sponsor
P
Praxis Spinal Cord Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study explores two promising therapies for restoring arm and hand function in people with chronic cervical spinal cord injury (SCI), a condition that affects independence and quality of life. It will compare transcutaneous spinal cord stimulation and paired corticospinal-motoneuronal stimulation, both combined with rehabilitation. Using a crossover design, participants will receive each therapy for two months, with a one-month washout period in between. Safety, effectiveness, and patient-reported outcomes like daily living ability and quality of life will be assessed, alongside changes in neural excitability. The results of this study may enable us to tailor treatments to individual needs, promoting personalized care and improved outcomes.
CONDITIONS
Official Title
Non-Invasive Neuromodulation for Upper Extremity Function in Spinal Cord Injury: A Crossover Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Cervical (C2-C8) level spinal cord injury
- More than 9 months since injury
- Traumatic spinal cord injury
- AIS grade A to D
- Stable dose of anti-spasmodic medications
You will not qualify if you...
- Injury to the nervous system other than the spinal cord
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Glenrose Rehabilitation Hospital
Edmonton, Alberta, Canada, T5G0B7
Actively Recruiting
Research Team
J
Jessica M D'Amico, PhD
CONTACT
C
Caitlin Hurd, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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