Actively Recruiting
Non-invasive Phrenic Nerve Stimulation in ARDS Patient
Led by Southeast University, China · Updated on 2024-08-27
10
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Reduced diaphragmatic activity during mechanical ventilation can lead to diaphragmatic disuse atrophy, atelectasis, increased lung stress and strain, and hemodynamic impairment. This, in turn, may prolong the duration of mechanical ventilation, make weaning more difficult, and even increase mortality. Synchronizing phrenic nerve stimulation to promote diaphragmatic activity may prevent ventilator-induced lung injury and ventilator-induced diaphragm dysfunction, thereby improving patient outcomes. Surgically implanted phrenic nerve stimulation has been used in certain neurological disorders, but the effects of percutaneous non-invasive synchronized phrenic nerve stimulation in patients with ARDS undergoing mechanical ventilation remain unclear and require further investigation.
CONDITIONS
Official Title
Non-invasive Phrenic Nerve Stimulation in ARDS Patient
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult ARDS patients undergoing controlled mechanical ventilation
- Duration of endotracheal intubation less than 48 hours
You will not qualify if you...
- Neurological condition affecting motor neuron or muscle (e.g. ALS)
- Paralysis of the phrenic nerve
- Proven or suspected spinal cord injury
- Conditions that limit diaphragm movement
- Patients with implanted cardiac support systems (pacemaker, implanted defibrillator)
- Patients with implanted medical pumps
- Pregnancy
- Patients with skin lesions, infections, or strictures in throat/neck area
- Patients with metallic implants
- Refusal to sign informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Zhongda Hospital, School of Medicine, Southeast University
Nanjing, Jiangsu, China, 210009
Actively Recruiting
Research Team
L
ling liu, phD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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