Actively Recruiting
Non-invasive Preoperative Tissue Evaluation in Head and Neck Tumor Patients Using Multispectral Optoacoustic Tomography (MSOT)
Led by University of Erlangen-Nürnberg Medical School · Updated on 2024-12-04
40
Participants Needed
1
Research Sites
35 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Multispectral Optoacoustic Tomography (MSOT) is a promising imaging technology that utilizes pulsed laser light. One of the key capabilities of this technology is measuring oxygenation within human tissue. This proposed study aims to investigate possible limitations of human tissue used for reconstructive surgery due to flawed tissue perfusion. Healthy volunteers as well as patients with a diagnosed head and neck cancer entity will be recruited. Both cohorts will then be scanned on different body areas (most common tissue sites used for reconstructive surgery on the back, arms and legs) to assess differences in muscle oxygenation between the healthy and tumor patient cohort using MSOT. The hypothesis of the study is, that patients with diagnosed head and neck cancer entities are prone to compromised tissue perfusion due to a high prevalence of smoking within the head neck tumor patient cohort and therefore perfusion restirciting diseases e.g. peripheral arterial occlusive disease (PAOD).
CONDITIONS
Official Title
Non-invasive Preoperative Tissue Evaluation in Head and Neck Tumor Patients Using Multispectral Optoacoustic Tomography (MSOT)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histopathologically diagnosed head and neck tumor patients (Cohort 1)
- Healthy adults (Cohort 2)
You will not qualify if you...
- Pregnancy or breastfeeding
- Presence of tattoos or ink in areas of interest (upper back, distal forearm, upper and lower leg)
- Missing consent form
- Chronic abuse of alcohol and nicotine (Cohort 2)
AI-Screening
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Trial Site Locations
Total: 1 location
1
University Hospital Erlangen
Erlangen, Bavaria, Germany, 91054
Actively Recruiting
Research Team
F
Felix Wachter
CONTACT
J
Jonas Wolf, Dr. med.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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