Actively Recruiting
Non-invasive Stimulation of Deep Brain Structures to Modulate Working Memory
Led by Masaryk University · Updated on 2026-05-01
70
Participants Needed
1
Research Sites
17 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A study investigating the effects of non-invasive electrical stimulation of deep brain structures on working memory, attention, and executive functions involved in everyday activities. Currently, there is no effective treatment for impairments in these functions. The study will evaluate the effects of non-invasive electrical stimulation in both healthy older adults and individuals with mild impairment of these functions. The study combines magnetic resonance imaging (MRI) with non-invasive brain stimulation targeting deep brain structures. Its aim is to improve understanding of the neural mechanisms underlying these cognitive functions and their impairments, as well as to explore the mechanisms of non-invasive brain stimulation for potential future therapeutic applications.
CONDITIONS
Official Title
Non-invasive Stimulation of Deep Brain Structures to Modulate Working Memory
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 60 and 80 years
- Normal cognitive performance for healthy participants as assessed by cognitive screening
- Diagnosis of possible or probable mild cognitive impairment related to Lewy body disease or Parkinson's disease, meeting level II criteria based on neuropsychological exams and clinical features
You will not qualify if you...
- Presence of psychiatric disorders including major depression
- Major vascular lesions or other brain conditions that may cause cognitive decline
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
CEITEC Masaryk University
Brno, Czechia, 612 00
Actively Recruiting
Research Team
M
Monika Pupíková
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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