Actively Recruiting
Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain Fog
Led by Mayo Clinic · Updated on 2025-11-10
45
Participants Needed
1
Research Sites
83 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to assess the effects of both acute and chronic exposures to hypoxia and hypercapnia in patients with Long COVID syndrome.
CONDITIONS
Official Title
Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain Fog
Who Can Participate
Eligibility Criteria
You may qualify if you...
- English speaking
- Diagnosis of Long COVID
You will not qualify if you...
- History of coronary artery dissection or aortic dissection
- History of neurological diseases such as dementia, Alzheimer's disease, or other brain-related diseases
- History of cerebrovascular disease or stroke
- History of aneurysm
- Currently have moderate to severe chronic obstructive pulmonary disease
- Currently have uncontrolled moderate to severe asthma
- Currently have moderate to severe bronchiectasis
- Currently have moderate to severe interstitial lung disease requiring supplemental oxygen
- Need to use supplemental oxygen for any reason
- New or worsening heart failure symptoms
- Right heart disease due to chronic lung disease or sleep apnea
- Uncontrolled myocardial ischemia or angina
- Uncontrolled heart arrhythmias
- Heart or lung infections like myocarditis or pericarditis
- Left main coronary artery stenosis
- Moderate to severe aortic stenosis
- Pulmonary embolism, pulmonary infarction, or other blood clots
- Severe respiratory disease
- Chronic kidney disease
- Chronic liver disease
- Female participants of childbearing potential must have a negative pregnancy test at baseline
- Body mass index over 40
- Inability of study staff to obtain adequate cerebral blood flow signal
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic in Arizona
Scottsdale, Arizona, United States, 85259
Actively Recruiting
Research Team
J
Jordan Parks
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
8
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