Actively Recruiting

Phase Not Applicable
Age: 18Years - 85Years
All Genders
NCT04767074

A Non-pharmacological Cough Control Therapy

Led by West Park Healthcare Centre · Updated on 2025-04-03

24

Participants Needed

2

Research Sites

273 weeks

Total Duration

On this page

Sponsors

W

West Park Healthcare Centre

Lead Sponsor

S

St. Joseph's Healthcare Hamilton

Collaborating Sponsor

AI-Summary

What this Trial Is About

Coughing affects almost all individuals with ILD leading to physical, psychological and social distress and prevents individuals from performing their activities of daily living, working or socialising in public places. Unfortunately, there are no licensed medications available to treat chronic cough and the few drugs that have been tried resulted in little efficacy and significant side effects. Drug-free cough control interventions have shown promise in reducing the severity and impact of coughing on patients' lives but have not been tested in individuals with ILD. This study aims to explore the feasibility and effectiveness of a non-pharmacological cough control therapy, as an adjuvant of pulmonary rehabilitation, in patients with ILD and chronic cough (\>8 weeks in duration).

CONDITIONS

Official Title

A Non-pharmacological Cough Control Therapy

Who Can Participate

Age: 18Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed diagnosis of any interstitial lung disease (ILD) by a physician
  • Chronic cough lasting more than 8 weeks
  • Age between 18 and 85 years
Not Eligible

You will not qualify if you...

  • Moderate or large sputum production reported by the patient
  • Respiratory condition exacerbation in the past month
  • Upper respiratory tract infection in the past month
  • Use of angiotensin-converting enzyme inhibitor medication
  • Changes in prescribed medication in the previous month
  • Evidence of traction bronchiectasis on HRCT scan
  • Medical conditions preventing exercise training
  • Inability to read or speak English or provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

St. Joseph's Healthcare Hamilton

Hamilton, Ontario, Canada

Actively Recruiting

2

West Park Healthcare Centre

Toronto, Ontario, Canada, M6M 2J5

Actively Recruiting

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Research Team

A

Ana Oliveira, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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