Actively Recruiting

Phase Not Applicable
Age: 18Years - 85Years
All Genders
ID04767074

A Non-pharmacological Cough Control Therapy as an Adjuvant of Pulmonary Rehabilitation in People With Interstitial Lung Diseases and Chronic Cough - A Feasibility Study

Led by West Park Healthcare Centre · Updated on 2025-04-03

24

Participants Needed

2

Research Sites

N/A

Total Duration

On this page

Sponsors

W

West Park Healthcare Centre

Lead Sponsor

S

St. Joseph's Healthcare Hamilton

Collaborating Sponsor

AI-Summary

What this Trial Is About

Coughing is a common and distressing symptom for people with interstitial lung disease (ILD), affecting daily activities, work, and social life. This research explores a non-drug cough control therapy combined with pulmonary rehabilitation to see if it is practical and helps reduce chronic cough lasting more than eight weeks in ILD patients. The study aims to assess how well patients accept this therapy and whether it improves quality of life, cough symptoms, and fatigue compared to standard pulmonary rehabilitation alone. Participants will join a pulmonary rehabilitation program involving aerobic and strengthening exercises, disease-specific education, and self-management as usual care. Two weeks before finishing this program, they will receive four virtual sessions of 45 to 60 minutes each, focusing on cough control education and techniques. These sessions include assessing cough, learning suppression methods, breathing retraining, and reinforcing strategies to manage cough in daily life. During the study, researchers will track enrollment and attendance to measure feasibility, along with various clinical outcomes like cough severity questionnaires, fatigue scales, breathlessness ratings, and patient satisfaction interviews. The intervention is delivered online via Zoom, allowing remote participation. The total study duration averages one year, with ongoing assessments to understand the therapy's impact and participants' experiences.

CONDITIONS

Brief Title

A Non-pharmacological Cough Control Therapy

Who Can Participate

Age: 18Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 85 years
  • Confirmed diagnosis of any interstitial lung disease (ILD) by a physician
  • Chronic cough lasting more than 8 weeks in duration
Not Eligible

You will not qualify if you...

  • Moderate or large sputum production
  • Recent exacerbation of respiratory condition within the past month
  • Upper respiratory tract infection in the past month
  • Use of angiotensin-converting enzyme inhibitor medication
  • Changes in prescribed medication within the previous month
  • Evidence of traction bronchiectasis in high-resolution CT scan
  • Other medical conditions preventing exercise training program participation
  • Unable to read or speak English or provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or virtual) for eligibility assessment

Pulmonary Rehabilitation

Duration - Variable duration prior to cough control therapy start

Participants join a pulmonary rehabilitation program composed of aerobic and strengthening exercises, disease-specific education, and self-management as part of their usual care.

Virtual sessions as part of routine care

Non-pharmacological Cough Control Therapy

Duration - Approximately 4 weeks (four sessions)

Participants attend four virtual educational and self-management sessions focusing on cough assessment, cough control techniques, breathing pattern retraining, and reinforcement of cough control strategies.

4 virtual sessions of 45 to 60 minutes each

Follow-up and Outcome Assessment

Duration - Up to 1 year from study enrollment

Participants complete outcome assessments including questionnaires and interviews to evaluate feasibility, cough symptoms, quality of life, fatigue, and satisfaction with the cough control therapy.

Periodic virtual assessments during follow-up

Trial Site Locations

Total: 2 locations

1

St. Joseph's Healthcare Hamilton

Hamilton, Ontario, Canada

Actively Recruiting

2

West Park Healthcare Centre

Toronto, Ontario, Canada, M6M 2J5

Actively Recruiting

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Research Team

A

Ana Oliveira, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Published Research Related To This Trial

Physiotherapy, and speech and language therapy intervention for patients with refractory chronic cough: a multicentre randomised control trial.

Sarah A F Chamberlain Mitchell, Rachel Garrod, Lynne Clark...

https://pubmed.ncbi.nlm.nih.gov/27682331