Actively Recruiting
Non-pharmacological Treatment vs Pharmacological Treatment for Non-acute Lumbar Disc Herniation
Led by Jaseng Medical Foundation · Updated on 2025-09-11
200
Participants Needed
4
Research Sites
385 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a randomized controlled study comparing non-pharmacological treatment to proactive pharmacological treatment for patient with non-acute lumbar disc herniation with moderate or higher levels of pain. The study involves 200 adult patients aged 19-69, with 50 patients from each participating hospital. Patients will be randomly assigned to either the non-pharmacological treatment group or the pharmacological treatment group 1:1 ratio. Specific interventions will be determined by doctors and Korean medicine doctors without predefined treatment strategies. The non-pharmacological treatment include acupuncture, electroacupuncture, spinal manual therapy and motion style acupuncture. The pharmacological treatment include medication prescription, injection, and nerve block. Treatment period is 8 weeks, and f/u for 3 years.
CONDITIONS
Official Title
Non-pharmacological Treatment vs Pharmacological Treatment for Non-acute Lumbar Disc Herniation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 19 to 69 years
- Lower back pain lasting at least 1 month
- Numeric Rating Scale score of 5 or higher for lower back or radiating leg pain over the past 3 consecutive days
- Confirmed lumbar disc herniation on MRI explaining the pain
- Provided written informed consent to participate
You will not qualify if you...
- Diagnosed with serious diseases causing back or leg pain such as spinal metastasis, acute fractures, or spinal dislocation
- Progressive neurological deficits or severe neurological symptoms
- Pain from soft tissue disorders other than the spine like tumors or fibromyalgia
- Chronic conditions like stroke, myocardial infarction, renal disease, diabetic neuropathy, dementia, or epilepsy that may affect treatment
- Taking steroids, immunosuppressants, psychiatric medications, or other drugs affecting study results
- Conditions making acupuncture or nerve block unsafe, including bleeding disorders, anticoagulant use, or uncontrolled diabetes
- Used NSAIDs, pain medications, or acupuncture within 5 days before the study
- Pregnant, planning pregnancy, or breastfeeding
- Within 3 months after lumbar surgery
- Participated in another clinical study within the past month or planning to participate in one during this study or follow-up
- Unable to provide written informed consent
- Other conditions deemed by researchers to make participation difficult
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Jaseng Hospital of Korean Medicine
Seoul, Gangnam-Gu, South Korea, 135-896
Actively Recruiting
2
Bucheon Jaseng Hospital of Korean Medicine
Bucheon-si, Gyeonggi-do, South Korea, 14598
Actively Recruiting
3
Haeundae Jaseng Hospital of Korean Medicine
Busan, South Korea
Actively Recruiting
4
Daejeon Jaseng Hospital of Korean Medicine
Daejeon, South Korea
Actively Recruiting
Research Team
I
In-Hyuk Ha, Dr
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here