Actively Recruiting
Non-specific Effects of a Modified Measles Vaccination Schedule to Prevent Allergy and Unrelated Infection in Children
Led by Laure Pittet, MD-PhD · Updated on 2024-05-29
500
Participants Needed
1
Research Sites
193 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to evaluate the off-target/non-specific effects of the measles-mumps-rubella (MMR) vaccine in children.
CONDITIONS
Official Title
Non-specific Effects of a Modified Measles Vaccination Schedule to Prevent Allergy and Unrelated Infection in Children
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent
- Child is 6 months old
- Child is in overall good health without significant diseases such as kidney failure, liver dysfunction, or heart disease
- Child is fully immunised for age according to the Swiss vaccination schedule, including at least 2 doses of DTP-containing vaccine
- The last vaccine dose was received at least 2 weeks before enrollment
You will not qualify if you...
- Immunosuppression or suspected immunosuppression
- Allergy to any component of the MMR vaccine
- Receipt of a live-attenuated vaccine within 4 weeks before enrollment
- Refusal of vaccination
- Indication for early MMR vaccination due to measles outbreak, planned immunosuppression, or travel to high-risk areas
- Need for MMR-varicella vaccination instead of MMR, including severe eczema or parental request
- Inability of parent or guardian to follow study procedures due to language, psychological, compliance, or substance abuse issues
- Planned move out of country or prolonged absence during the trial
- More than one sibling in the trial (only one child from multiple pregnancy can enroll)
- Temporary contraindication to MMR such as active illness at the time of enrollment
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University Hospitals of Geneva
Geneva, Switzerland, 1211
Actively Recruiting
Research Team
L
Laure F Pittet, MD-PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
PREVENTION
Number of Arms
4
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