Actively Recruiting

Phase 1
Phase 2
All Genders
Healthy Volunteers
NCT06467318

Does Non-Steroidal Anti-inflammatory Drugs Decrease the Quality of Pleurodesis After Mechanical Pleural Abrasion/Pleurectomy for Treatment of Pneumothorax?

Led by Ain Shams University · Updated on 2024-06-21

116

Participants Needed

1

Research Sites

65 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Investigators aim to assess if NSAIDs affect the quality of pleurodesis resulting from mechanical pleurodesis (open surgery or VATS) regarding : Primary outcome: Recurrence of pneumothorax in 6 monthes. (assessed by X ray after 2 weeks and 6 months or symptoms requiring X ray at any timing) Secondary outcome: ▪ Adjusted Length of stay ( from day zero surgery day to discharge ). ▪ Time of removal of the chest Tube .(relatively longer with air leak presence). ▪ Need of opioids (N-SAID may decrease the need of opioids) .

CONDITIONS

Official Title

Does Non-Steroidal Anti-inflammatory Drugs Decrease the Quality of Pleurodesis After Mechanical Pleural Abrasion/Pleurectomy for Treatment of Pneumothorax?

Who Can Participate

All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with primary or secondary spontaneous pneumothorax
  • All age groups are eligible
  • Undergoing mechanical pleurodesis by open surgery or video-assisted thoracoscopic surgery (VATS)
Not Eligible

You will not qualify if you...

  • Patients who refuse the procedure or participation in the study
  • Any contraindication to NSAIDs such as bleeding tendency, chronic kidney disease, gastritis, or allergy to NSAIDs

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Faculty of medicine, Ain shams university

Cairo, Egypt, 1181

Actively Recruiting

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Research Team

H

Hany Hassan, Professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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Does Non-Steroidal Anti-inflammatory Drugs Decrease the Quality of Pleurodesis After Mechanical Pleural Abrasion/Pleurectomy for Treatment of Pneumothorax? | DecenTrialz