Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06973135

Non-Surgical Single Visit Endodontic Retreatment in Cases With Asymptomatic Apical Periodontitis Using Bioceramic Sealer

Led by Saly Nazeer · Updated on 2025-05-15

70

Participants Needed

2

Research Sites

113 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if using bioceramic sealers in non surgical single visit endodontic retreatment in patients with endodontic treatment failure and asymptomatic apical periodontitis will work in comparison to other resin sealer which proved efficacy ,and help healing of the periapical lesions and reduce the anticipated postoperative pain , Participants will have root canal retreatment done in a single visit and then follow up will be done in 1, 3 and 6 months to check healing and then after 12 months , also postoperative pain will be monitored through communicating the patients after 24, 28 , 72 hours and the 7 days

CONDITIONS

Official Title

Non-Surgical Single Visit Endodontic Retreatment in Cases With Asymptomatic Apical Periodontitis Using Bioceramic Sealer

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Mandibular molar teeth with previous unsuccessful endodontic treatment for at least 1 year and asymptomatic apical periodontitis
  • Teeth with inadequate root canal filling
  • Teeth with broken instruments that can be bypassed or removed and are not in the apical third or passing through the apex
  • Teeth showing periapical lesions
  • Patients aged 18 to 65 years
  • Medically healthy patients or those with mild controlled systemic disease (ASA I or II)
  • No acute pain or swelling outside the mouth
  • Patients willing to participate and attend follow-up visits
Not Eligible

You will not qualify if you...

  • Teeth needing retreatment with poor prognosis (altered root canal shape, large cavities, internal/external root resorption, or root perforation)
  • Teeth with vertical root fractures or open apex
  • Patients with systemic bone metabolism disorders or taking drugs affecting bone metabolism
  • Pregnant patients
  • Patients treated with antibiotics within 2 weeks before the study
  • Patients unable to attend follow-up visits

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

faculty of dentistry Alexandria university

Alexandria, Egypt, 0000

Actively Recruiting

2

faculty of dentistry Alexandria university

Alexandria, Egypt, 0000

Actively Recruiting

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Research Team

S

sally M Nazir, Master

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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