Actively Recruiting
Noninvasive Brain Stimulation in Adult Amblyopia
Led by Midwestern University · Updated on 2024-12-12
60
Participants Needed
1
Research Sites
243 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this randomized controlled trial is to investigate the effectiveness of non-invasive brain stimulation in treating adults with amblyopia. The main questions it aims to answer are: 1. What are the effects of non-invasive brain stimulation on neuronal plasticity in the visual cortex of adults with amblyopia, and does it produce lasting changes? 2. Do cumulative sessions of non-invasive brain stimulation influence neural plasticity and higher-order visual functions in adults with amblyopia? The investigators hypothesize that non-invasive brain stimulation will show a positive cumulative effect after five (5) consecutive days of stimulation on visual perception and function in adults with amblyopia. Participants will be randomized into one of two treatment groups: 1. High-frequency transcranial random noise stimulation (hf-tRNS). 2. Sham stimulation. Researchers will compare baseline measurements of crowded visual acuity, contrast sensitivity, stereoacuity, phosphene thresholds, global motion perception, form pattern recognition and pattern-reversal visual evoked potentials (VEPs) to post-treatment measurements for each group.
CONDITIONS
Official Title
Noninvasive Brain Stimulation in Adult Amblyopia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults between 18 and 55 years of age
- Formal diagnosis of amblyopia in one or both eyes of any etiology
You will not qualify if you...
- History of optic nerve disease, including glaucoma and optic neuritis
- History of neurological conditions, including demyelinating disease or stroke
- Presence of metal or electronic implants in or on the body, including pacemakers
- Taking medications that can affect normal neurological function, including antipsychotics, antiepileptics, and opioids
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Midwestern University Eye Institute
Downers Grove, Illinois, United States, 60515
Actively Recruiting
Research Team
A
Arijit Chakraborty, PhD
CONTACT
A
Adrienne C Quan, OD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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