Actively Recruiting

Phase Not Applicable
Age: 60Years - 80Years
All Genders
NCT03895541

Noninvasive Elastography Evaluation of Myocardial Stiffness in Elderly Patients With Isolated Diastolic Heart Failure: New Diagnostic Tool?

Led by French Cardiology Society · Updated on 2025-03-11

90

Participants Needed

1

Research Sites

309 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The new approach propose in this protocol is based on ultrafast ultrasound and remote palpation of tissue by ultrasonic radiation pressure. Ultrafast ultrasound of biological tissues is based on an innovative ultrasound imaging approach that can image very fast soft tissue events at a rate of several thousands of frames per second and provide quantitative mapping of the elasticity of the tissues. This current project aims is to focus on myocardial rigidity in diastole to better assess the function of the heart failure.

CONDITIONS

Official Title

Noninvasive Elastography Evaluation of Myocardial Stiffness in Elderly Patients With Isolated Diastolic Heart Failure: New Diagnostic Tool?

Who Can Participate

Age: 60Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Hospitalization in cardiology services for acute pulmonary edema during heart failure
  • B-type natriuretic peptide level of 35 pg/ml or higher
  • Echocardiographic structural alteration
  • Left ventricular ejection fraction 50% or higher (preserved LVEF group)
  • Left ventricular ejection fraction between 40% and 49% (moderate alteration group)
  • Left ventricular ejection fraction below 40% (systolic heart failure group)
Not Eligible

You will not qualify if you...

  • Other associated lung pathology
  • Other heart disease
  • Contraindication to MRI or echocardiography gel
  • Pregnancy
  • Poor echogenicity

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Emmanuel MESSAS

Paris, France, 75015

Actively Recruiting

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Research Team

E

Emmanuel MESSAS, MD

CONTACT

T

Tessa BERGOT

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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