Actively Recruiting

Age: 18Years - 45Years
FEMALE
Healthy Volunteers
NCT06343974

Noninvasive Evaluation of Fetal Hyperinsulinemia With Ultrasound Radiomics

Led by Turku University Hospital · Updated on 2025-11-28

60

Participants Needed

2

Research Sites

85 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to compare fetal liver ultrasound radiomics between pregnancies complicated by type 1 diabetes and healthy controls. The main questions it aims to answer are: * Are fetal liver ultrasound radiomic features reproducible? * Does fetal liver ultrasound radiomics differ between pregnancies complicated by type 1 diabetes and healthy controls? Participants will undergo ultrasound examination to collect ultrasound data for the analyses.

CONDITIONS

Official Title

Noninvasive Evaluation of Fetal Hyperinsulinemia With Ultrasound Radiomics

Who Can Participate

Age: 18Years - 45Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18-45 years
  • Able to give informed consent
  • Singleton pregnancy
  • Planning to deliver at Turku University Hospital
  • Maternal BMI less than 40
  • Gestational age confirmed by first trimester ultrasound
  • Normal oral glucose tolerance test (OGTT) at 24-28 weeks of pregnancy in controls
Not Eligible

You will not qualify if you...

  • Major fetal chromosomal, genetic, or structural anomaly
  • Fetal growth restriction or birth weight below 10th percentile
  • Birth weight above 90th percentile or polyhydramnios in controls
  • Non-reassuring fetal status requiring immediate treatment or intrauterine fetal death
  • Verified fetal infection such as cytomegalovirus, toxoplasma, hepatitis B or C (excluding bacterial infection from intrapartum chorioamnionitis)
  • Placenta accreta spectrum disorder
  • Major maternal medical condition requiring systemic drug treatment except non-severe hypertension, hypothyroidism, asthma, mild psychiatric disorders
  • Alcohol, tobacco use, or substance abuse during pregnancy

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Turku University Hospital

Turku, Finland

Actively Recruiting

2

Turku University Hospital

Turku, Finland

Actively Recruiting

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Research Team

M

Mikael Huhtala, M.D., Ph.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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