Actively Recruiting

Age: 18Years - 90Years
All Genders
ID05652023

Noninvasive Ultrasound Assessment of Detrusor Dysfunction

Led by Mayo Clinic · Updated on 2026-03-27

2023

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating a new ultrasound method called Quantitative Ultrasound Bladder Vibrometry (QUBV) to detect abnormal bladder function, specifically focusing on detrusor overactivity and benign prostatic hyperplasia (BPH) treatment selection. This observational study aims to assess how well QUBV works as a noninvasive tool compared to urodynamic studies, which are part of participants' regular clinical care. Participants will undergo QUBV ultrasound at the same time as their scheduled urodynamic study or selective photovaporization of the prostate, depending on their diagnosis and treatment plan. The study will include adults aged 18 to 90 years who are already scheduled for these procedures as part of their clinical care. The research will not involve experimental treatments but will observe and compare QUBV results with standard diagnostic methods. During the study, researchers will measure the accuracy of QUBV in determining detrusor pressure and in selecting BPH patients for surgery. Data will be collected up to study completion, averaging one year. Participants will continue with their usual care, and the study involves no additional interventions beyond the ultrasound measurement performed alongside routine procedures.

CONDITIONS

Brief Title

Noninvasive Ultrasound Assessment of Detrusor Dysfunction

Who Can Participate

Age: 18Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 18 years and scheduled to undergo urodynamic study for bladder dysfunction, overactive bladder, or BPH with urinary obstruction
  • Age over 45 years and scheduled for selective photovaporization of the prostate
Not Eligible

You will not qualify if you...

  • Obesity with body mass index over 35 kg/m2
  • Known neurological diseases impacting bladder function such as spinal cord injury, multiple sclerosis, Parkinson's disease, or prior cerebrovascular accident
  • Previous pelvic radiation therapy
  • Previous radical pelvic surgery such as for uterine or colorectal cancer
  • Prior bladder surgery including prostate resection
  • Pregnant or breast-feeding women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Up to study completion, an average of 1 year

Participants undergo a quantitative ultrasound bladder vibrometry (QUBV) performed at the same time as a urodynamic study as part of their regular clinical care to assess detrusor overactivity and aid in treatment selection.

1 visit (in-person)

Long-term Monitoring

Duration - Up to study completion, an average of 1 year

Participants are observed over time to evaluate the accuracy of ultrasound vibrometry for measuring bladder function and selecting appropriate treatment.

Follow-up visits as part of routine clinical care

Trial Site Locations

Total: 1 location

1

Mayo Clinic

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

A

Azra Alizad, MD

K

Kathryn (Katie) Barthels

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Frequently Asked Questions

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