Norwegian Study Comparing Small-Bite Suture Technique Alone Versus With Onlay Mesh to Prevent Hernias After Midline Laparotomy Surgery

What this Trial Is About

Researchers are evaluating techniques to prevent incisional hernias, a common complication after midline laparotomy surgery, where abdominal contents can protrude through a surgical scar. This trial compares the use of a small-bite suture technique alone versus the same suture technique combined with an additional onlay polypropylene mesh to reinforce the abdominal wall. The study aims to improve understanding and encourage use of mesh in Norway where its use is currently limited. Participants undergoing midline laparotomy at three Norwegian hospitals will be randomly assigned to one of two groups. One group will have their abdomen closed using the small-bite suture method plus an onlay polypropylene mesh, with a subcutaneous drain to help prevent fluid buildup. The other group will receive closure using only the small-bite suture technique. The study will track outcomes after surgery to compare these approaches. Participants will be followed for one year after surgery. Researchers will assess the presence of incisional hernias using clinical exams and CT scans at 12 months. Additional assessments include surgical site complications such as hematoma, infection, seroma, and wound issues at 4 to 6 weeks post-surgery. Quality of life and pain will also be evaluated at both 4 to 6 weeks and one year. This information will help determine which closure method better reduces hernia risk and improves recovery.

NoPro - Norwegian Hernia Prophylaxis Study