Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06858020

NoPro - Norwegian Hernia Prophylaxis Study

Led by Sykehuset Innlandet HF · Updated on 2025-03-05

150

Participants Needed

1

Research Sites

197 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A multicenter randomized controlled trial comparing midline laparotomy closures using the small-bite suture technique alone to those using the small-bite suture technique with an additional onlay prophylactic polypropylene mesh. The primary endpoint is the incidence of incisional hernias in both groups after one year.

CONDITIONS

Official Title

NoPro - Norwegian Hernia Prophylaxis Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Surgery predominantly done by midline laparotomy
  • Age 18 years old or older
  • Written consent by patient or family
  • Midline laparotomy with delayed closure
  • No exclusion criteria
Not Eligible

You will not qualify if you...

  • Age under 18 years
  • Pregnancy
  • Previous abdominal midline hernia mesh repair
  • Abdominal compartment syndrome
  • Linea alba closure not possible
  • Life expectancy under six months
  • Hernia in the midline with transverse diameter larger than 2 cm

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Innlandet Hospital Trust

Hamar, Norway

Actively Recruiting

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Research Team

G

Gjertrud H Kjostolfsen, MD

CONTACT

J

Jorunn Skattum, MD PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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