Actively Recruiting

Phase Not Applicable
All Genders
ID07500116

NORA-HOME Efficiency And Safety An Ambulatory Multimodal Monitoring Model In Patients With Minor Stroke And Transient Ischemic Attacks

Led by Hospital Universitari Vall d'Hebron Research Institute · Updated on 2026-03-30

250

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

H

Hospital Universitari Vall d'Hebron Research Institute

Lead Sponsor

V

Vall Hebron Insitut Recerca

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating a Home Hospitalization program called NORAHOME for patients who have had a transient ischemic attack (TIA) or a minor stroke. The study aims to determine if this multimodal home care approach is safe, reduces complications linked to traditional hospital stays, and is more efficient than standard clinical practice. Patients with TIA or minor stroke are at higher risk of stroke recurrence, and current early evaluations often require hospital admission, which can be costly and risky. In this study, patients who come to the Emergency Department with TIA or minor stroke are randomly assigned to either the NORAHOME home hospitalization program or conventional hospital care. The home hospitalization group receives close monitoring and care at home, while the control group undergoes standard hospital admission. The study includes a 3-month follow-up period where outcomes for both groups are compared to assess safety, efficiency, and patient experience. Participants will be monitored for complications such as falls, infections, and stroke recurrence. Assessments include patient-reported health outcomes and experiences, control of vascular risk factors, adherence to treatment, and evaluations of daily living activities. The study also uses diagnostic tests like focused echocardiography and remote cardiac monitoring. Safety and effectiveness are evaluated at 15 days and 3 months, with the total study participation lasting 3 months after enrollment.

CONDITIONS

Brief Title

NORA-HOME: An Ambulatory Multimodal Monitoring Model In Patients With Minor Stroke And Transient Ischemic Attacks

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients presenting to the Emergency Department with symptoms of TIA (complete recovery within <24 hours) or minor stroke (NIHSS 64 5)
  • Age >18 years
  • Availability of a smartphone for the patient or caregiver
  • Family support and/or formal caregiver
  • Clinical stability during the last 12 hours in the Emergency Department
  • Signed informed consent by the patient and/or family member or legal representative
Not Eligible

You will not qualify if you...

  • Severe stenosis or symptomatic arterial occlusion requiring admission for potential reperfusion or arterial revascularization treatments
  • Pre-existing neurological or psychiatric conditions that may interfere with follow-up and evaluations
  • Clinical (terminal condition) or social (language barrier) inability to complete follow-up assessments

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person) at the Emergency Department for initial assessment and consent

Home Hospitalization

Duration - 3 months

Participants randomized to the NORAHOME program receive ambulatory multimodal monitoring and care for their minor stroke or TIA at home.

Ongoing remote monitoring with scheduled in-person visits as needed during the 3-month period

Conventional Hospitalization

Duration - 3 months

Participants randomized to standard clinical practice receive conventional hospitalization and care for their minor stroke or TIA.

Hospital stay and follow-up visits according to standard clinical practice during the 3-month period

Follow-up and Outcome Assessment

Duration - Up to 3 months post-randomization

Participants in both groups are followed for safety, efficacy, and patient-reported outcomes to compare the two care models after the initial intervention period.

Scheduled follow-up visits and assessments to evaluate safety, recurrence risk, and patient experience

Trial Site Locations

Total: 1 location

1

Vall Hebron University Hospital

Barcelona, Spain, 08035

Actively Recruiting

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Research Team

M

Marian Muchada Lopez, MD, PHD

M

Marta Rubiera del Fueyo, MD, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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