Creating a Normative Database of Retinal Vascular Density in Healthy Adults Using Spectralis Heidelberg Optical Coherence Tomography Angiography

What this Trial Is About

Researchers are creating a normative database of retinal microvascular density using the Spectralis Heidelberg optical coherence tomography angiography OCT-A device in healthy adults. OCT-A allows non-invasive imaging of retinal and choroidal blood vessels without dye injection and is useful in studying various eye and systemic conditions like diabetes and age-related macular degeneration. Since different OCT-A devices provide varying measurements, this study aims to establish device-specific normal values for Caucasian individuals using the Heidelberg OCT-A. Participants will undergo optical coherence tomography angiography and a comprehensive eye exam to measure vascular density in different layers of the retina and choroid. The study focuses on assessing the vascular density of the superficial capillary plexus, deep capillary plexus, and choriocapillaris in both macular and peripapillary zones. These assessments will be completed during a single study visit. During the visit, participants will receive an ophthalmological examination including intraocular pressure measurement and OCT-A imaging. Researchers will evaluate the quality of the OCT-A scans and confirm vascular density parameters. The main outcomes measured are vascular density values from these retinal layers, which will be analyzed to build a normative reference. Participants are healthy volunteers and the study involves no treatment or follow-up visits beyond the initial assessment.

Normative Database of Healthy Subject Vascular Density Using Spectralis Heidelberg® Optical Coherence Tomography Angiography