Actively Recruiting

Age: 18Years +
All Genders
NCT03890614

Novel 3D Hematological Malignancy Organoid to Study Disease Biology and Chemosensitivity

Led by Wake Forest University Health Sciences · Updated on 2026-03-20

70

Participants Needed

1

Research Sites

402 weeks

Total Duration

On this page

Sponsors

W

Wake Forest University Health Sciences

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The objective of this project is to compare chemosensitivity between chemotherapy combinations in bone marrow aspirates using 3D organoid models. The investigators overarching hypothesis is that 3D organoids are ideal to test chemosensitivity in real time, to provide personalized medicine and guidance in the setting of relapsed hematologic malignancy and potentially other cancers.

CONDITIONS

Official Title

Novel 3D Hematological Malignancy Organoid to Study Disease Biology and Chemosensitivity

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with suspected or confirmed hematologic malignancy undergoing a bone marrow biopsy as part of their care.
  • Ability to understand and willingness to sign an IRB approved informed consent document.
Not Eligible

You will not qualify if you...

  • None specified.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Wake Forest Baptist Comprehensive Cancer Center

Winston-Salem, North Carolina, United States, 27157

Actively Recruiting

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Research Team

S

Study Coordinator

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Novel 3D Hematological Malignancy Organoid to Study Disease Biology and Chemosensitivity | DecenTrialz