Actively Recruiting
Novel Amblyopia Treatment With Virtual Reality Games
Led by Marjean Kulp · Updated on 2025-07-22
8
Participants Needed
1
Research Sites
146 weeks
Total Duration
On this page
Sponsors
M
Marjean Kulp
Lead Sponsor
B
Beta Sigma Kappa - College of Optometrists in Vision Development
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this study is to compare the change in amblyopic eye acuity between treatment periods in children with amblyopia, aged 5-17 years. The main question it aims to answer is: Is a 16-week course of amblyopia treatment using Vivid Vision Therapeutic (Dichoptic) Virtual Reality Games for approx. 25 min/day, 6 days/week more effective for improvement in amblyopic-eye VA, binocularity (stereoacuity, suppression, alignment), contrast sensitivity, attention, oculomotor function, visual-motor integration, and quality of life than 16 weeks of continued glasses alone? Participants will each serve as their own control and complete: Treatment period 1: Continued optical correction (glasses) alone for 16 weeks; Treatment period 2: Vivid Vision Therapeutic (Dichoptic) Virtual Reality Games for 16 weeks (approx. 25min/day, 6 days/week) plus continued optical correction
CONDITIONS
Official Title
Novel Amblyopia Treatment With Virtual Reality Games
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients ages 5 to 17 years of age
- Moderate to severe unilateral amblyopia with logMAR best corrected visual acuity 0.3 to 1.3
- Amblyopia associated with anisometropia and/or strabismus of 45 prism diopters or less
- Normal vision in the nonamblyopic eye for age
- Worn spectacle correction for at least 16 weeks or until stable visual acuity demonstrated (less than 0.1 logMAR change on 2 exams at least 8 weeks apart)
- Interocular difference of 3 or more lines
- No amblyopia treatment in the past 2 weeks
- Interpupillary distance between 52 and 72 mm inclusive
You will not qualify if you...
- Myopia greater than -6.00 diopters spherical equivalent in either eye
- Previous intraocular or refractive surgery
- Previous dichoptic treatment longer than 2 weeks
- Ocular conditions that may reduce visual acuity, except nystagmus if visual acuity criteria are met
- Diplopia more than once per week in the last week before enrollment
- Diagnosis of Down syndrome or cerebral palsy
- History of light-induced seizures
- Known simulator sickness
- Severe developmental delay interfering with treatment or evaluation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Ohio State University College of Optometry
Columbus, Ohio, United States, 43210
Actively Recruiting
Research Team
M
Marjean T Kulp, OD, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here