Actively Recruiting
Novel Biochemical and Molecular Determinants for Soft Tissue Sarcoma
Led by Memorial Sloan Kettering Cancer Center · Updated on 2025-07-30
3000
Participants Needed
7
Research Sites
1252 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to study normal and sarcoma cells. To study these cells we need to have human tissue. You will be having or have already had a procedure to remove tissue. We would like to use some of this tissue. We will use it for laboratory studies on the diagnosis,behavior and treatment of sarcoma. We will perform an extensive analysis of your samples. We will only use extra tissue left over after all needed testing has been done or remove an additional small amount of tissue if you are having a biopsy. We will also take blood samples before and/or after your procedure to measure biochemical factors that may help us predict the behavior of sarcoma.
CONDITIONS
Official Title
Novel Biochemical and Molecular Determinants for Soft Tissue Sarcoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- All patients with known or suspected sarcoma who will have or have had tissue removed for therapeutic or diagnostic purposes.
- Patients will be entered without preference for any particular racial/ethnic group or gender.
- Patients may have received prior hormonal therapy, cytotoxic chemotherapy, irradiation, immunotherapy or surgical therapy.
- Tissue specimens must be large enough in quantity to allow routine pathologic analysis, with the research laboratory specimen removed from the residual specimen, which would otherwise be discarded.
- Optimal tissue amounts for snap freeze: Core biopsy - 2 tissue cores; Incisional biopsy - 0.5 to 1.5 grams; Resected sarcoma specimen - 1.0 to 50 grams depending on size of specimen; Normal fat or muscle tissue - 0.5 to 4.0 grams (if available from resected sarcoma specimen).
- Optimal tissue amounts for RNA later: Core biopsy - 2 tissue cores; Incisional biopsy - 30 mg (three 3 x 3 x 3 mm cubes); Resected sarcoma specimen - 30 mg (three 3 x 3 x 3 mm cubes); Normal fat or muscle tissue - 30 mg (three 3 x 3 x 3 mm cube)
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
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Trial Site Locations
Total: 7 locations
1
Memorial Sloan Kettering Basking Ridge (Consent and Follow-Up)
Basking Ridge, New Jersey, United States, 07920
Actively Recruiting
2
Memorial Sloan Kettering Monmouth (Consent and Followup)
Middletown, New Jersey, United States, 07748
Actively Recruiting
3
Memorial Sloan Kettering Bergen (Consent and Follow up)
Montvale, New Jersey, United States, 07645
Actively Recruiting
4
Memorial Sloan Kettering Commack (Consent and Follow-Up)
Commack, New York, United States, 11725
Actively Recruiting
5
Memorial Sloan Kettering Westchester (Consent and Followup)
Harrison, New York, United States, 10604
Actively Recruiting
6
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, United States, 10065
Actively Recruiting
7
Memorial Sloan Kettering Nassau (Consent and Followup)
Rockville Centre, New York, United States, 11553
Actively Recruiting
Research Team
S
Samuel Singer, MD
CONTACT
A
Aimee Crago, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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