Actively Recruiting
Novel Cavity Marking Technique in Breast Cancer Patients Undergoing Breast Conservation Surgery With Oncoplastic Reconstruction for the Delivery of Adjuvant Radiotherapy and Accuracy of Recommended Re-excisions
Led by University of Florida · Updated on 2025-12-15
50
Participants Needed
1
Research Sites
209 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will investigate a novel approach to marking surgical cavity margins following tumor resection, to allow for more accurate radiotherapy following oncoplastic surgery. Our proposed cavity marking schema will allow radiation oncology to identify the cavity margins more accurately on CT simulation for radiation planning and delivery. This cavity marking schema also provides more accurate margin identification in patients recommended for re-excision of close or positive margins.
CONDITIONS
Official Title
Novel Cavity Marking Technique in Breast Cancer Patients Undergoing Breast Conservation Surgery With Oncoplastic Reconstruction for the Delivery of Adjuvant Radiotherapy and Accuracy of Recommended Re-excisions
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 63 18 years of age.
- Pathological diagnosis of non-invasive ductal carcinoma in-situ (DCIS) or invasive breast cancer, Tis-T3N0-3M0.
- Planning to undergo or have undergone breast conservation surgery with oncoplastic reconstruction and cavity marking.
- ECOG Performance status of 0-1.
- Written informed consent provided and agreement to comply with study procedures.
- No more than one active malignancy at enrollment (exceptions possible if approved).
- Subjects of childbearing potential must use adequate contraception during surgery and radiation therapy and be informed of pregnancy risks.
You will not qualify if you...
- Patient not recommended for or has declined adjuvant radiotherapy.
- Prior ipsilateral breast surgery with identifiable surgical clips.
- Confirmed pregnancy or breastfeeding.
- Any other disease or condition that contraindicates study treatment or risks complications, as judged by the treating physician.
- Prisoners, involuntarily incarcerated individuals, or those compulsorily detained for psychiatric or physical illness.
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Trial Site Locations
Total: 1 location
1
University of Florida
Gainesville, Florida, United States, 32608
Actively Recruiting
Research Team
S
Stephanie Portillo
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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