Study of a New Dental Gel Used with Scaling and Root Planing to Treat Stage II and III Periodontitis

What this Trial Is About

Researchers are evaluating the use of Livionex Dental Gel LDG as a home care product alongside standard scaling and root planing SRP treatment to reduce probing pocket depth in patients with stage II and III periodontitis. This randomized, single-blind study aims to assess whether LDG can provide additional benefits in controlling plaque and improving gum health beyond the effects of SRP alone. The study is sponsored by the University of Alabama at Birmingham and focuses on adult participants with moderate to advanced periodontal disease. Participants receive SRP at the start of the study to physically remove plaque, tartar, and bacterial toxins from affected teeth. They are then assigned to use either LDG or a standard fluoride toothpaste twice daily for six months. Both dentifrices are used with toothbrushing for two minutes each time. LDG contains an ingredient called EDTA that may prevent bacterial plaque from sticking to teeth, which is being studied for its potential to reduce plaque and gingival inflammation. During the study, participants will have their gum health monitored through measurements like probing pocket depth, gingival index, plaque index, and bleeding on probing at baseline and after six months. Researchers will also track adherence to the brushing routine and evaluate safety throughout the trial. The total participation time is six months, during which oral hygiene and periodontal status are regularly assessed to understand the impact of the dental gels when used as part of daily home care.

Novel Dental Gel as an Adjunct to Scaling and Root Planing