Actively Recruiting
Novel Dental Gel as an Adjunct to Scaling and Root Planing
Led by University of Alabama at Birmingham · Updated on 2025-12-17
76
Participants Needed
1
Research Sites
315 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will evaluate the use of Livionex Dental Gel (LDG) as a home care product in reducing probing pocket depth (PD) beyond the effect achieved by the current standard of care with SRP in periodontitis patients.
CONDITIONS
Official Title
Novel Dental Gel as an Adjunct to Scaling and Root Planing
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female subjects at least 18 years of age
- Willing and able to provide written informed consent
- Available during the course of the study
- Have a minimum of 20 natural teeth, excluding third molars
- Have at least 20 bleeding on probing (BOP) sites, excluding third molars
- Diagnosed with stage II or III, Grade B periodontitis with at least 4 teeth having a probing depth (PD) of 5 mm or more and clinical attachment loss (CAL) of 3 mm or more
- No antibiotic therapy for periodontal disease or chronic use of anti-inflammatory drugs within the past month or during the study
- No definitive treatment for periodontitis such as scaling and root planing or periodontal surgery within the last year
- Willing and able to comply with study visits as described in the protocol
- Available for follow-up by telephone
- Able to read and understand the consent form in English
You will not qualify if you...
- Pregnancy or breastfeeding
- Medical condition requiring pre-medication before dental procedures
- Systemic conditions or medications affecting periodontal tissues
- Severe dental disease with multiple decayed or untreated sites
- Presence of orthodontic appliances
- Diseases of oral soft or hard tissues
- Participation in another clinical trial currently or within the past month
- Stage IV and/or Grade C periodontitis
- Vertical bone defects of 4 mm or greater
- Active dental infections other than periodontitis requiring treatment during the study
- Excessive oral hygiene practices such as use of water irrigation devices or interdental cleaners more than twice daily
- Non-English speaking
- Smokers, uncontrolled or brittle diabetics, HIV/AIDS, or severe systemic diseases like cancer, lupus, or oral mucous membrane diseases interfering with oral hygiene
- History of allergic reaction to any ingredient in the test or control dentifrices
- Any condition at baseline that may prevent compliance with study requirements
- Unwillingness to use a manual toothbrush during the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Unversity of Alabama at Birmingham, School of Dentistry
Birmingham, Alabama, United States, 35294-0007
Actively Recruiting
Research Team
M
Maninder Kaur, BDS,MPH,MS
CONTACT
S
Sarah Startley, DMD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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