Actively Recruiting

Age: 18Years - 95Years
All Genders
NCT07528781

Novel 3-dimensional Echocardiographic Quantification of Mitral Regurgitant Volume

Led by Germans Trias i Pujol Hospital · Updated on 2026-04-14

200

Participants Needed

1

Research Sites

106 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is demonstrate that a novel artificial intelligence based software for the quantification of the mitral regurgitation on 3-dimensional transesophageal echocardiography (3D CFQ) is more reproducible and accurate than the conventional assessment of mitral regurgitation performed with 2-dimensional echocardiography. The main question aims to answer is to demonstrate the agreement between 3D-CFQ measurement of the mitral regurgitant volume and the cardiac magnetic resonance measurement of the regurgitant volume is better than the agreement between 2-dimensional echocardiography and cardiac magnetic resonance. If this is demonstrated, we would like to test the accuracy of this tool to be applied in acute settings such as transcatheter interventions to decide the therapy to follow. Participants will undergo clinically indicated transesophageal echocardiography to characterize the mechanism and severity of mitral regurgitation and to cardiac magnetic resonance to be used as reference stadard to define the mitral regurgitation severity.

CONDITIONS

Official Title

Novel 3-dimensional Echocardiographic Quantification of Mitral Regurgitant Volume

Who Can Participate

Age: 18Years - 95Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with at least moderate mitral regurgitation of any etiology
  • Patients with good transesophageal echocardiography image quality
Not Eligible

You will not qualify if you...

  • Patients with prior transcatheter or surgical mitral valve intervention
  • Patients with contraindications for transesophageal echocardiography or cardiac magnetic resonance

AI-Screening

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Trial Site Locations

Total: 1 location

1

Hospital University Germans Trias i Pujol

Badalona, Barcelona, Spain, 08916

Actively Recruiting

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Research Team

V

Victoria Delgado, Head of Cardiovascular Imaging department, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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