Actively Recruiting
Novel Echocardiographic Biomarkers Assessing the Myocardial Work in Heart Failure
Led by Aristotle University Of Thessaloniki · Updated on 2024-07-31
300
Participants Needed
1
Research Sites
143 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study seeks to investigate the clinical value of novel echocardiographic indices, including myocardial work parameters, during the acute phase of heart failure hospitalization. The trajectory of novel echocardiographic indices from the start to the end of hospitalization will be captured, as a means to unravel and subsequently better understand the diverse pathophysiology of different phenotypes of the heart failure continuum. Correlation between novel echocardiographic indices with clinical data, biochemical data, different heart failure phenotypes, and therapeutic maneuvers will be attempted. Prognostic implications of those indices will be explored.
CONDITIONS
Official Title
Novel Echocardiographic Biomarkers Assessing the Myocardial Work in Heart Failure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients acutely admitted at the Department of Cardiology of AHEPA University General Hospital, Thessaloniki, Greece with symptoms and/or signs of heart failure as defined by the European Society of Cardiology
- Patients with abnormal plasma concentration of N-terminal pro-B-type natriuretic peptide measured within 24 hours from admission
- Objective echocardiographic evidence of cardiac structural and/or functional abnormalities consistent with left ventricular systolic dysfunction, diastolic dysfunction, or raised left ventricular filling pressures upon admission
You will not qualify if you...
- Symptoms and/or signs of heart failure secondary to congenital heart disease, infective endocarditis, pericardial disease, or recent cardiac surgery within 1 month
- Patients receiving maintenance hemodialysis
- Patients with active malignancy or life expectancy less than 1 year
- Poor echocardiographic acoustic windows preventing reliable assessment or analysis
- History of heart transplantation
- Patients not providing informed written consent to participate in the study
AI-Screening
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Trial Site Locations
Total: 1 location
1
AHEPA University Hospital, Thessaloniki, Greece
Thessaloniki, Central Macedonia, Greece, 54621
Actively Recruiting
Research Team
S
Stylianos Daios, MD, MSc
CONTACT
V
Vasileios Anastasiou, MD, MSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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