Actively Recruiting
Novel Epigenetic Mapping in Cell-Free DNA for the Detection of Lung Cancer
Led by JaxBio Ltd · Updated on 2025-05-09
300
Participants Needed
1
Research Sites
78 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This trial is a multicenter, open-label, non-interventional controlled study to identify and characterize epigenetic signatures of lung cancer. The goal of this study is to develop a simple blood test that can detect lung cancer with high sensitivity, and assist in the early diagnosis and management of lung cancer. In particular, the ability to assist existing methods in cancer diagnostics, predict response to treatment, and assess the success of treatment during and after treatment will be examined. In addition, the ability to assess minimal residual disease (MRD) will be evaluated, by taking blood after surgery to remove a tumor or after treatment, and testing whether there is any residual DNA from the tumor using the markers that are found. The collection of patients and data will be conducted over a period of about a year and a half, with the aim of reaching approximately 300 participants, including patients with lung cancer before and after treatment/surgery and control groups.
CONDITIONS
Official Title
Novel Epigenetic Mapping in Cell-Free DNA for the Detection of Lung Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women over 18 years old
- Patients diagnosed with lung cancer before systemic therapy
- Patients with inconclusive low-dose CT scan findings
- Healthy volunteers
- Patients with chronic lung diseases such as COPD, pulmonary emphysema, or acute pneumonia
You will not qualify if you...
- Individuals who did not sign a consent form
- Patients with cancers other than lung cancer
- Patients with HIV or hepatitis
- Patients with active autoimmune diseases except lung-localized diseases
- Pregnant women or individuals unable to give informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sheba Medical Center
Ramat Gan, Israel
Actively Recruiting
Research Team
Y
Yael Michaeli, Ph.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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