Actively Recruiting
A Novel Intervention for Weight Loss in Young Adults Combining Behavioral Coaching and Technology
Led by University of Chicago · Updated on 2025-11-17
140
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of Chicago
Lead Sponsor
N
Northwestern University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are investigating how combining a behavioral intervention with technology may impact weight loss in young adults who are overweight or obese. This study aims to address the public health challenges of obesity and related cardiometabolic risks by exploring new effective strategies for weight loss. The trial focuses on adults aged 18 to 40 years who have stable weight and are interested in using digital tools to support their goals. Participants will be involved in a 6-month program where they receive diet and exercise coaching from trained professionals. They will regularly record their weight using a digital scale, track their daily food intake through a smartphone app, and wear a wrist activity monitor to measure physical activity. The intervention includes up to five daytime clinic visits with blood draws and surveys, and personalized guidance from a coach to help maintain progress. Throughout the study, participants will attend scheduled visits to provide blood samples and complete questionnaires while their weight and activity data are continuously monitored. The primary measure is weight loss from the start of the study to six months. Safety and adherence will be tracked, and participants will be supported in their lifestyle changes during the entire period of involvement.
CONDITIONS
Brief Title
A Novel Intervention for Weight Loss in Young Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Overweight or obese men and women with BMI between 25.5 and 34.9 kg/m2
- Ages 18 to 40 years
- Stable weight with no change greater than 25 pounds in the past 3 months
- Owns a smartphone and willing to install the study app
You will not qualify if you...
- Obstructive sleep apnea or any other sleep disorder
- Irregular menstruation, menopausal symptoms, post-menopausal, pregnant, trying to conceive, or nursing
- Regular travel across time zones
- Currently following a weight loss or special diet or exercise program
- Increased lean body mass such as athletes
- Unable to walk, uses mobility assistive devices, or has contraindications to exercise
- Diabetes
- Claustrophobia
- Excessive alcohol (more than 2 drinks/day), caffeine (more than 300mg/day), regular nicotine use, or substance abuse
- Abnormal screening blood test results
- Taking medications or supplements affecting sleep or weight
- Major psychiatric or eating disorders, acute or chronic medical conditions increasing intervention risks including heart disease, pulmonary disease, cancer treatment in past 5 years, infections, thyroid or endocrine disorders, gastrointestinal diseases, renal disease, significant anemia, recent or significant abdominal surgery, acute coronary syndrome or stroke in past 6 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Approximately 6 months
Participants receive diet and exercise goals and coaching, paired with a trained coach. They regularly record their weight using a digital scale, input daily food intake into a smartphone app, and wear a wrist activity monitor to track physical activity.
Up to 5 visits (in-person) involving daytime clinic visits with fasted blood draws and surveys
Trial Site Locations
Total: 1 location
1
University of Chicago
Chicago, Illinois, United States, 60637
Actively Recruiting
Research Team
O
Olivia Hughes
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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