Assessing Liver Regeneration and Predicting Related Complications Using Carbon Monoxide Measurement After Partial Liver Surgery

What this Trial Is About

Researchers are studying how the body produces carbon monoxide CO after part of the liver has been surgically removed. The study focuses on measuring CO levels in breath as a way to understand how well the liver regenerates and to predict possible liver-related complications after surgery. This research aims to better monitor liver healing and assess liver function following surgery. All participants will provide breath samples to measure carbon monoxide levels before surgery, then again 4 hours and 24 hours after liver resection. The study will track these CO levels alongside the amount and quality of liver regeneration over time. Liver volume and function will be assessed at one and three months after the surgery to correlate with the CO measurements. Participants will be monitored through breath tests and follow-up visits to measure liver regeneration and function. Researchers will collect data on CO levels in exhaled air and compare them to liver volume and function results. The main outcome is to find a link between CO levels and liver healing, which may help predict liver-related health issues after surgery. The study is expected to continue until 2039.

Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy