Actively Recruiting
Novel Skin Barrier Product Versus Petrolatum for Skin Barrier Dysfunction
Led by Makati Medical Center · Updated on 2025-09-19
26
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if a novel barrier topical product works to treat barrier dysfunction in adults. It will also learn about the safety of the novel barrier topical product. The main questions it aims to answer are: Does the novel barrier topical product improve skin hydration, skin sebum, redness, and pigmentation? Does it improve subjective dryness and itch? Researchers will compare the novel barrier topical product to petrolatum (a gold standard occlusive barrier repair agent) to see how they are comparable in treating skin barrier dysfunction. Participants will: Apply the novel barrier topical product or petrolatum twice a day for 28 days Visit the clinic once a week for checkups and tests Keep a diary of their application of the assigned product
CONDITIONS
Official Title
Novel Skin Barrier Product Versus Petrolatum for Skin Barrier Dysfunction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults with a clinical diagnosis of mild skin barrier dysfunction including mild to moderate atopic dermatitis (SCORAD 50) not requiring topical corticosteroids or immunomodulators
- Mild to moderate chronic plaque psoriasis involving 3% to 10% of total body surface area
- Diagnosis of contact dermatitis
- Seasonal xerosis or clinically evident skin dryness
- Presence of symmetrical or bilateral test areas on the volar forearm
- Willing and able to provide informed consent and follow study procedures
You will not qualify if you...
- Severe atopic dermatitis or psoriasis requiring systemic or high-potency topical treatments
- Use of corticosteroids, calcineurin inhibitors, biologics, or phototherapy within the past 2 weeks
- Open wounds or signs of secondary infection at the test sites
- Pregnant or breastfeeding women
- Multiple nevi, tattoos, or dense body hair in the test areas
- Being debilitated or immunocompromised
- Known or suspected allergy to the study product or petrolatum
- Refusal or inability to comply with scheduled study visits
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
VMV Skin Research Center & Clinics
Makati City, National Capital Region, Philippines, 1229
Actively Recruiting
Research Team
C
Cristina C Verallo Rowell, MD, MBA
CONTACT
V
Vermen M Verallo-Rowell, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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