Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06676085

A Novel Strategy of ECMO Management Using Nafamostat for Regional Combined With Low Intensity Systematic Anticoagulation

Led by Beijing Chao Yang Hospital · Updated on 2024-11-18

60

Participants Needed

1

Research Sites

165 weeks

Total Duration

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AI-Summary

What this Trial Is About

ECMO is widely used in patients with refractory respiratory and/or circulatory failure.The data shows that the incidence of bleeding and thrombotic events is still above 40%,and it is closely related to the increase in mortality rate.Therefore, optimizing ECMO anticoagulation management to reduce bleeding and thrombotic events is a key scientific issue that urgently needs to be addressed.

CONDITIONS

Official Title

A Novel Strategy of ECMO Management Using Nafamostat for Regional Combined With Low Intensity Systematic Anticoagulation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age older than 18 years old
  • Received ECMO because of severe respiratory failure
Not Eligible

You will not qualify if you...

  • Anticoagulant contraindications
  • Cerebral infarction or suspected patients
  • Severe hypertension
  • Women in gestational and lactational period
  • Hemophilia
  • Allergic to heparin or Nafamostat
  • Unwilling or unable to complete the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Bing Sun

Beijing, Beijing Municipality, China, 100020

Actively Recruiting

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Research Team

B

Bing Sun, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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