Actively Recruiting
Developing New Surgical Guidelines for Degenerative Cervical Myelopathy in Chinese Adults Aged 45 and Older
Led by The University of Hong Kong · Updated on 2026-05-20
100
Participants Needed
1
Research Sites
286 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Degenerative Cervical Myelopathy DCM is an age-related condition mainly affecting people aged 50 and over, caused by changes in the spine like ligament ossification or disc problems that compress the cervical spinal cord. It leads to symptoms such as hand numbness, clumsiness, and difficulty walking. This research aims to develop new surgical criteria based on physical performance tests alongside MRI and clinical signs to better guide surgery decisions for DCM, focusing on the Chinese population. The study involves confirming DCM diagnosis using MRI and orthopedic surgeon evaluation. Researchers will use physical performance tests such as the 10-second Grip and Release test, 10-second Stepping Test, and Foot Tapping Test over 24 months to assess functional deficits. These tests, combined with clinical indicators and MRI findings, will help establish objective criteria to predict the need for surgery. Participants will be evaluated regularly for their physical abilities and neurological function using these performance tests. The study will monitor changes over 24 months to assess hand and gait coordination. Researchers will also use clinical signs and patient cognitive ability to understand symptom progression. The goal is to improve surgical decision-making and recovery outcomes by identifying clear physical performance benchmarks in DCM patients.
CONDITIONS
Brief Title
A Novel Surgical Criteria for Degenerative Cervical Myelopathy in Chinese Ethnicity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- MRI confirmed Chinese DCM surgical candidates
- All gender
- Older than 45 years old
- Independent walkers
- No previous cervical spinal surgery
- Cognitively capable of following instructions
You will not qualify if you...
- Active diagnosis of tuberculosis spine
- Lumbar spinal diseases
- Extra-pyramidal disorders
- Cerebral or cerebellar disorders
- Peripheral neuropathies
- Previous spinal operations
- Unable to walk independently with or without aids
- Non-communicable subjects and cognitively incapable of expressing their symptoms clearly
Research Team
K
Karlen Ka-pui Law, M. Phil
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