Actively Recruiting
Novel Telemedicine-Delivered Prolonged Exposure Therapy for Treating PTSD in Individuals With OUD
Led by University of Vermont · Updated on 2025-04-13
135
Participants Needed
1
Research Sites
182 weeks
Total Duration
On this page
Sponsors
U
University of Vermont
Lead Sponsor
N
National Institute on Drug Abuse (NIDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Among individuals with opioid use disorder (OUD), posttraumatic stress disorder (PTSD) presents a significant clinical challenge. The prevalence of PTSD is substantially higher in individuals with OUD than in the general population, with nearly 90% reporting lifetime trauma exposure and 33% meeting diagnostic criteria for PTSD. The primary objective of this study is to evaluate the efficacy of a novel telemedicine-delivered prolonged exposure therapy protocol for improving PE attendance and reducing PTSD symptom severity in individuals with concurrent PTSD and OUD.
CONDITIONS
Official Title
Novel Telemedicine-Delivered Prolonged Exposure Therapy for Treating PTSD in Individuals With OUD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Over 18 years old
- Maintained on a stable methadone or buprenorphine dose for more than 1 month prior to the study
- Meet current DSM-5 criteria for posttraumatic stress disorder based on a clinical assessment
- If taking psychotropic medications, dose must be stable for more than 1 month before enrollment
You will not qualify if you...
- Current delusions or hallucinations, unstable bipolar disorder, or imminent risk of suicide
- Cognitive impairment indicated by a low score on a videoconference-based mental status exam
- Currently enrolled in another ongoing evidence-based treatment for PTSD
- Pregnancy as confirmed by a pregnancy test
- No access to cellular service
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Vemont
Burlington, Vermont, United States, 05401
Actively Recruiting
Research Team
K
Kelly Peck, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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