Actively Recruiting
Improving Treatment of Childhood Lung Infections Using Lung Ultrasound to Guide Antibiotic Use in Children Aged 2 Months to 12 Years
Led by University of Bern · Updated on 2025-06-18
3500
Participants Needed
9
Research Sites
17 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are evaluating how using lung ultrasound can help improve treatment decisions for children aged 2 months to 12 years who have symptoms of a lung infection. The study focuses on better identifying which children actually need antibiotics, aiming to reduce unnecessary antibiotic use that can cause health problems and contribute to antibiotic resistance. Lung infections are a leading cause of illness in children and are often treated with antibiotics even when caused by viruses, which do not respond to these drugs. Participants are randomly assigned to one of two groups one receiving routine care without additional testing, and the other receiving lung ultrasound examinations. In the ultrasound group, experts review images to guide doctors on whether antibiotics are needed, potentially reducing antibiotic prescriptions if the infection appears viral. The study excludes children who are very sick or have already taken antibiotics for more than two days. The study also evaluates lung ultrasounds role in diagnosing tuberculosis and other lung conditions. During the study, children are assessed at the start and followed up through day 29 or 8 weeks depending on the outcomes measured. This includes monitoring antibiotic use, clinical improvement, hospital admissions, adverse reactions, and diagnoses like tuberculosis. Researchers collect data through clinical exams, ultrasound imaging, and other tests as needed. The goal is to see if lung ultrasound can safely reduce antibiotic use without harming health outcomes, with careful safety monitoring throughout the study period.
CONDITIONS
Brief Title
Novel Tools to Improve Management of Paediatric Community-Acquired Pneumonia - ToolCAP
Research Team
K
Kristina Keitel, MD, PhD
J
Jacques du Toit, MD
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here