Actively Recruiting

Phase Not Applicable
Age: 18Years - 44Years
FEMALE
NCT05382403

Novel Vacuum-Induced Hemorrhage Control for Postpartum Hemorrhage

Led by Women and Infants Hospital of Rhode Island · Updated on 2023-12-21

424

Participants Needed

2

Research Sites

183 weeks

Total Duration

On this page

Sponsors

W

Women and Infants Hospital of Rhode Island

Lead Sponsor

W

Washington University School of Medicine

Collaborating Sponsor

AI-Summary

What this Trial Is About

This will be the first, definitive, randomized control trial (N=424) to test the hypothesis that the Jada® System is effective, safe and cost-effective in treating PPH, compared to standard care.

CONDITIONS

Official Title

Novel Vacuum-Induced Hemorrhage Control for Postpartum Hemorrhage

Who Can Participate

Age: 18Years - 44Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years or older
  • Delivery at 34 weeks or greater
  • Cumulative blood loss >1000ml within 24 hours after delivery
  • Uterine atony
  • Receipt of first-line uterotonics
  • Cervix at least 3cm dilated at cesarean section
Not Eligible

You will not qualify if you...

  • Patient unwilling or unable to provide informed consent
  • Retained placenta or other known cause of postpartum hemorrhage
  • Placenta accreta spectrum
  • Coagulopathy
  • Rupture uterus
  • Surgical management immediately needed for life-threatening bleeding
  • Known contraindication for Jada System; ongoing intrauterine pregnancy, untreated uterine rupture, unresolved uterine inversion, current cervical cancer, unknown uterine anomaly, current purulent infection

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Komfo Anokye Teaching Hospital

Kumasi, Ashanti Region, Ghana

Actively Recruiting

2

Korle-bu Teaching Hospital

Accra, Greater Accra Region, Ghana

Actively Recruiting

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Research Team

C

Crystal Ware, BSN, CCRP

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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