Actively Recruiting
A Novel Volume Stable Matrix for Gingival Recession Coverage at Teeth
Led by University of Bern · Updated on 2026-02-27
60
Participants Needed
1
Research Sites
256 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Periodontal health and preservation of the dentition without tooth loss are important quality of life components and should be safeguarded in order to provide optimal function and esthetics. Optimal treatment of gingiva recessions is likely to allow for more efficient use of healthcare resources and reduced costs long-term. It is evident that the prevalence in gingival recession is high and its consequences on the aging population constitute an important healthcare issue that requires further attention. The standard therapy of gingival recession encompasses a coronally advanced flap or coronally advanced tunnel flap and a connective tissue graft from the palate. Harvesting of the palatal graft involves a second surgical site and increased morbidity for the patients.This project aims to compare the connective tissue graft against a novel volume stable collagen matrix. Patients will be treated according to standard protocols of the Department of Periodontology. In the test group patient will undergo tissue thickening with a collagen matrix and the modified coronally advanced tunnel technique. The control group will undergo the standard protocol using a connective tissue graft from the palate along with the modified coronally advanced tunnel technique. No study specific risks do exist.
CONDITIONS
Official Title
A Novel Volume Stable Matrix for Gingival Recession Coverage at Teeth
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Written informed consent
- Healthy patients referred for recession coverage
- Miller Class I, II, or III facial gingival recession defect larger than 3 mm on the buccal side of maxillary or mandibular canines and incisors
You will not qualify if you...
- History of bleeding disorders or hypocoagulability
- Unstable diabetes mellitus
- Post-irradiation in head and neck area
- Infectious diseases
- Heart diseases needing prophylactic antibiotics before dental treatments
- Medication affecting gingiva such as Ciclosporin A, Phenytoin compounds, or calcium channel blockers
- Pregnant or breastfeeding patients
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Department of Periodontology
Bern, Switzerland, 3010
Actively Recruiting
Research Team
A
Anton Sculean, Prof
CONTACT
N
Nikolaos Pandis
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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