Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07437417

A Novel Volume Stable Matrix for Gingival Recession Coverage at Teeth

Led by University of Bern · Updated on 2026-02-27

60

Participants Needed

1

Research Sites

256 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Periodontal health and preservation of the dentition without tooth loss are important quality of life components and should be safeguarded in order to provide optimal function and esthetics. Optimal treatment of gingiva recessions is likely to allow for more efficient use of healthcare resources and reduced costs long-term. It is evident that the prevalence in gingival recession is high and its consequences on the aging population constitute an important healthcare issue that requires further attention. The standard therapy of gingival recession encompasses a coronally advanced flap or coronally advanced tunnel flap and a connective tissue graft from the palate. Harvesting of the palatal graft involves a second surgical site and increased morbidity for the patients.This project aims to compare the connective tissue graft against a novel volume stable collagen matrix. Patients will be treated according to standard protocols of the Department of Periodontology. In the test group patient will undergo tissue thickening with a collagen matrix and the modified coronally advanced tunnel technique. The control group will undergo the standard protocol using a connective tissue graft from the palate along with the modified coronally advanced tunnel technique. No study specific risks do exist.

CONDITIONS

Official Title

A Novel Volume Stable Matrix for Gingival Recession Coverage at Teeth

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Written informed consent
  • Healthy patients referred for recession coverage
  • Miller Class I, II, or III facial gingival recession defect larger than 3 mm on the buccal side of maxillary or mandibular canines and incisors
Not Eligible

You will not qualify if you...

  • History of bleeding disorders or hypocoagulability
  • Unstable diabetes mellitus
  • Post-irradiation in head and neck area
  • Infectious diseases
  • Heart diseases needing prophylactic antibiotics before dental treatments
  • Medication affecting gingiva such as Ciclosporin A, Phenytoin compounds, or calcium channel blockers
  • Pregnant or breastfeeding patients

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department of Periodontology

Bern, Switzerland, 3010

Actively Recruiting

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Research Team

A

Anton Sculean, Prof

CONTACT

N

Nikolaos Pandis

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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