Actively Recruiting
NovoMatrix in Gingival Recession Coverage: Case Series
Led by Semmelweis University · Updated on 2025-04-04
20
Participants Needed
1
Research Sites
84 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Twenty patients seeking treatment for gingival recession coverage, ranging from 20-70 years of age with multiple Miller Class I or II buccal gingival recessions (depth≥3 mm, at least 3 adjacent teeth) will be recruited for this study. Five patients within the study patient pool looking for further orthodontic or restorative treatment that requires removal of one single rooted tooth within the study site of interest will be selected for histological sample removal. All procedures performed in this study will be executed according to established routine protocols, with the exception of block biopsies of one hopeless tooth per patient (total of 5 patients) at 6 months.
CONDITIONS
Official Title
NovoMatrix in Gingival Recession Coverage: Case Series
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female, between 20-70 years of age, who request gingival augmentation or recession coverage.
- Subjects who are willing to sign an informed consent, participate and return for follow-up visits.
- Subjects without significant medical history and currently not on medications that might complicate treatment outcomes.
- Subjects demonstrating good oral hygiene (FMPS, FMBS less than 20%).
You will not qualify if you...
- Subjects who do not meet all the inclusion criteria or who will not cooperate with the protocol schedule.
- Subjects who received and failed a previously placed autogenous graft.
- Subjects who have significant untreated periodontal disease, caries, infection or chronic inflammation in the oral cavity within two adjacent tooth positions of the clinical trial area.
- Subjects who have used nicotine-containing products within 3 weeks prior to surgery.
- Subjects who are insulin-dependent diabetic or if their Hgb1c levels > 6.5%.
- Subjects who have had a history of malignancy within the past 5 years (except for basal or squamous cell carcinoma of the skin or in situ cervical carcinoma).
- Subjects who are nursing or pregnant.
- Subjects who are presently taking medications (except estrogen/progesterone therapy) or those who are undergoing treatment that in known to have an effect on bone turnover.
- Subjects who have diseases that affect bone metabolism (excluding idiopathic osteoporosis).
- Subjects with a history of an autoimmune disease, documented allergy or multiple allergies to any component of the agents used in this study.
- Acutely infected mucogingival defect site.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Semmelweis University, Faculty of Dentistry
Budapest, Hungary, 1088
Actively Recruiting
Research Team
B
Bálint Molnár, DMD
CONTACT
A
Andrea Dobos, DMD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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