Actively Recruiting

Early Phase 1
Age: 18Years +
All Genders
NCT03638999

NSAIDs Stent Study

Led by Washington University School of Medicine · Updated on 2025-12-22

36

Participants Needed

1

Research Sites

478 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a pilot study to (1) evaluate the effect of Ketorolac on inflammatory response and its impact on stent related symptoms in patients undergoing stent placement procedure and (2) assess feasibility of recruitment, randomization, assessment procedures and implementation of the study intervention.

CONDITIONS

Official Title

NSAIDs Stent Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Over 18 years of age and willing and able to provide informed consent
  • Patients with renal urolithiasis planning to undergo ureteral stent placement following ureteroscopic manipulation
Not Eligible

You will not qualify if you...

  • Patients requiring a bilateral stone procedure
  • Patients on chronic NSAIDs use (more than 15 days within 30 days prior), except daily Aspirin 81 mg
  • Patients on any steroid therapy
  • Patients with prescription anti-inflammatory drugs
  • Patients with gastrointestinal ulcers
  • Patients with ureteral obstruction or stricture unrelated to stone disease
  • Patients with untreated active urinary tract infection prior to procedure
  • Patients with preexisting indwelling ureteral stent
  • Patients who are pregnant or lactating
  • Patients with renal or liver impairment
  • Patients with disease, infection, or co-morbidity that makes enrollment inappropriate per investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Washington University

St Louis, Missouri, United States, 63110

Actively Recruiting

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Research Team

A

Alana Desai, MD

CONTACT

K

Karla Bergeron, CCRP

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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