Actively Recruiting

Age: 18Years +
All Genders
NCT06707519

NSCLC Liquid Biopsies and Exhaled VOC

Led by St. Joseph's Healthcare Hamilton · Updated on 2026-04-22

210

Participants Needed

1

Research Sites

256 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objective of the study is to determine the feasibility of recruiting participants and using sputum, Bronchoalveolar lavage (BAL) and exhaled Volatile Organic Compounds (VOC) in addition to blood, as biological samples for detecting mutations in extracted cell-free DNA in non-small cell lung cancer (NSCLC) patients, before and after surgery, and any recurrence within a 24-month postoperative follow-up period. This is a pilot feasibility study, proposed as a 24-month prospective, single-center, non-interventional, observational trial with NSCLC-adenocarcinoma patients indicated for resection surgery with curative intent.

CONDITIONS

Official Title

NSCLC Liquid Biopsies and Exhaled VOC

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient must be at least 18 years of age
  • Patient must be able to provide consent
  • Patients undergoing surgical resection with curative intent for non-small cell lung cancer at St. Joseph's Healthcare Hamilton and Firestone Institute for Respiratory Health.
Not Eligible

You will not qualify if you...

  • Surgery done without curative intent or in presence of metastatic disease
  • Presence of other malignancies
  • Patients with previously treated malignancy within 5 years prior to current surgery (excluding skin cancer).

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

St. Joseph's Healthcare Hamilton

Hamilton, Ontario, Canada, L8N 4A6

Actively Recruiting

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Research Team

L

Layla Halwagi, BSc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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