Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT04231565

Nucleoside (Acid) Analogues Treatment in Patients With Normal ALT and Positive HBVDNA.

Led by Third Affiliated Hospital, Sun Yat-Sen University · Updated on 2024-03-01

200

Participants Needed

1

Research Sites

369 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is to investigate the clinical efficacy and safety of Nucleoside (acid) analogues treatment in patients with normal Alanine Aminotransferase and positive Hepatitis B virus DNA.

CONDITIONS

Official Title

Nucleoside (Acid) Analogues Treatment in Patients With Normal ALT and Positive HBVDNA.

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Positive hepatitis B surface antigen and hepatitis B antibody for more than 0.5 year
  • Age from 18 to 65 years old
  • Serum Alanine Aminotransferase (ALT) ≤1×ULN for at least 12 weeks
  • Positive Hepatitis B virus (HBV)
  • No nucleotide/nucleoside analogues or interferon treatment in the past 6 months
Not Eligible

You will not qualify if you...

  • Other active liver diseases
  • Hepatocellular carcinoma or other malignancy
  • Pregnancy or lactation
  • Human immunodeficiency virus infection or congenital immune deficiency diseases
  • Severe diabetes or autoimmune diseases
  • Other important organ dysfunctions
  • Using glucocorticoid
  • Inability to follow-up
  • Investigator considers participation inappropriate

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Third Affiliated Hospital of Sun Yat-sen University

Guangzhou, Guangdong, China, 510630

Actively Recruiting

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Research Team

Q

Qiumin Luo, Doctor

CONTACT

L

Liang Peng, Doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Nucleoside (Acid) Analogues Treatment in Patients With Normal ALT and Positive HBVDNA. | DecenTrialz