Actively Recruiting
Nutrition and Exercise Interventions for Androgen Deprivation Therapy-Induced Obese Frailty in Elderly and Non-Elderly Survivors of Advanced Prostate Cancer
Led by Roswell Park Cancer Institute · Updated on 2026-05-07
50
Participants Needed
1
Research Sites
521 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This trial studies how well nutrition and exercise interventions work in reducing androgen deprivation therapy-induced obese frailty in prostate cancer survivors. Individualized nutrition and exercise advice for prostate cancer patients on androgen deprivation therapy may help to reduce obese frailty and change the levels of myokines in blood.
CONDITIONS
Official Title
Nutrition and Exercise Interventions for Androgen Deprivation Therapy-Induced Obese Frailty in Elderly and Non-Elderly Survivors of Advanced Prostate Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Biopsy-confirmed prostate adenocarcinoma of any stage or grade
- Prescribed or currently receiving continuous androgen deprivation therapy for less than 5 years
- Hemoglobin level greater than 11 g/dL
- Creatinine less than 1.5 times the upper limit of normal (ULN)
- AST or ALT less than 2 times ULN within 6 months prior to enrollment
- Liver function tests less than 2 times ULN
- Able to walk unassisted at least 100 meters (200 steps) or Eastern Cooperative Oncology Group (ECOG) performance status of 1 or less
- No contraindications to any part of the study, including aerobic exercise
- Able to read, write, and understand English and provide written consent
- Understands the investigational nature of the study and signs approved informed consent form before any study procedures
You will not qualify if you...
- Known severe chronic obstructive pulmonary disease (COPD), ischemic heart disease, congestive heart failure, or significant heart rhythm problems
- Limiting orthopedic, musculoskeletal, or psychological conditions as determined by a clinician
- Overall medical frailty as determined by a clinician
- Any condition preventing additional blood collection beyond standard care
- Unwilling or unable to follow study protocol requirements
- Any condition that makes the participant unsuitable for the study intervention according to the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Roswell Park Cancer Institute
Buffalo, New York, United States, 14263
Actively Recruiting
Research Team
E
Ellis Levine, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
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