Actively Recruiting
Nutrition Intervention for Pancreatic Cancer
Led by Children's Hospital of Philadelphia · Updated on 2026-05-07
18
Participants Needed
2
Research Sites
60 weeks
Total Duration
On this page
Sponsors
C
Children's Hospital of Philadelphia
Lead Sponsor
U
University of Pennsylvania
Collaborating Sponsor
AI-Summary
What this Trial Is About
Patients with pancreatic cancer (pancreatic ductal adenocarcinoma (PDAC) and pancreatic neuroendocrine tumor (NET)) commonly experience fat malabsorption due to exocrine pancreatic insufficiency (EPI) and leads to gastrointestinal (GI) symptoms, malnutrition, weight loss, and reduced quality of life (QoL). Current standard treatment, pancreatic enzyme replacement therapy (PERT), is limited by suboptimal adherence, high cost, and partial effectiveness to prevent fat malabsorption. The objective of the study is to assess the feasibility and maintenance of lipid absorption function of a structured lipid medical food (SLMF; Encala®) powder in subjects with PDAC and NET with EPI.
CONDITIONS
Official Title
Nutrition Intervention for Pancreatic Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with pancreatic ductal adenocarcinoma or pancreatic neuroendocrine tumor and aged 18 years or older
- Life expectancy of 4 months or more
- Receiving at least 60% of daily calories by oral or enteral tube feeding
- For NET patients, documented gastrointestinal dysfunction such as over 5% unintentional weight loss or changes in bowel movements confirmed by an oncologist
You will not qualify if you...
- Pregnant or breastfeeding
- Unable to eat food by mouth
- Allergy to soy lecithin product ingredients
- Psychosocial environment that may hinder study participation as confirmed by medical team
- Military service members, Reserve Service members, National Guard members, Department of Defense civilians, and DoD contractors
- Patients unable to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
2
University of Pennsylvania Abramson Cancer Center
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
Research Team
E
Edmond K Appiah, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
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